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GOLT1A Knockout Cell Lines

Gene: GOLT1A

Official Full Name: golgi transport 1Aprovided by HGNC

Gene Summary: Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Located in Golgi apparatus subcompartment; endoplasmic reticulum; and nuclear envelope. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26808 GOLT1A Knockout cell line (HCT 116) Human GOLT1A 1:2~1:4 Negative Online Inquiry
KO26809 GOLT1A Knockout cell line (A549) Human GOLT1A 1:3~1:4 Negative Online Inquiry

Background

GOLT1A Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to have the GOLT1A gene disrupted or completely knocked out. This product allows researchers to study the functional role of GOLT1A in various biological pathways, including its involvement in Golgi apparatus dynamics and trafficking processes. The knockout mechanism is typically achieved through CRISPR-Cas9 gene editing technology, which ensures precise alterations at the genomic level, leading to a complete loss of GOLT1A expression.

The primary function of the GOLT1A Gene Knockout Cell Lines is to serve as a robust tool for elucidating the biological significance of the GOLT1A protein, enabling scientists to investigate its contributions to cellular processes such as protein glycosylation, vesicular transport, and membrane dynamics. In research settings, these cell lines facilitate the exploration of disease models, particularly those related to metabolic disorders and certain types of cancer, effectively linking gene function to disease manifestation.

What sets these cell lines apart from traditional models is their specificity and precision. By eliminating GOLT1A expression, researchers can obtain clear insights into the cellular consequences of this gene's absence, enabling more accurate interpretations of experimental results. Moreover, these cell lines save valuable time and resources by providing a ready-to-use platform for functional studies without the need for complex gene editing procedures.

For researchers and clinicians, the ability to investigate gene function through a carefully established knockout model is invaluable. These cell lines streamline the assessment of therapeutic targets, advance our understanding of gene relationships, and pave the way for personalized medicine strategies. With our company's long-standing expertise in precision gene editing and extensive portfolio of biological products, we are committed to supporting the scientific community in their quest for knowledge and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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