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GOLPH3 Knockout Cell Lines

Gene: GOLPH3

Official Full Name: golgi phosphoprotein 3provided by HGNC

Gene Summary: The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a peripheral membrane protein of the Golgi stack and may have a regulatory role in Golgi trafficking. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17339 GOLPH3 Knockout cell line (HeLa) Human GOLPH3 1:3~1:6 Negative Online Inquiry
KO17340 GOLPH3 Knockout cell line (HCT 116) Human GOLPH3 1:2~1:4 Negative Online Inquiry
KO17341 GOLPH3 Knockout cell line (HEK293) Human GOLPH3 1:3~1:6 Negative Online Inquiry
KO17342 GOLPH3 Knockout cell line (A549) Human GOLPH3 1:3~1:4 Negative Online Inquiry

Background

GOLPH3 Gene Knockout Cell Lines are advanced cellular models engineered to specifically disrupt the GOLPH3 gene, which plays a pivotal role in the regulation of Golgi apparatus structure and function. By achieving a complete knockout of this gene, these cell lines allow researchers to investigate the biological consequences of GOLPH3 loss, offering insights into its involvement in disease mechanisms such as cancer, metabolic disorders, and viral infections.

The key functions of GOLPH3 encompass the orchestration of Golgi vesicle trafficking and the regulation of cellular signaling pathways, including those related to cell proliferation and apoptosis. By utilizing these knockout cell lines, scientists can elucidate the downstream effects associated with the absence of GOLPH3, enabling a better understanding of its functional implications in health and disease. The precise removal of this gene allows for rigorous testing of hypotheses in cellular biology and toxicology studies.

Scientifically, GOLPH3 Gene Knockout Cell Lines are invaluable tools in both research and clinical settings. They facilitate the identification of novel therapeutic targets by allowing researchers to observe the functional ramifications of GOLPH3 deficiency. This can lead to the discovery of new biomarkers for disease and ultimately inform treatment strategies that could mitigate the impact of GOLPH3-related pathologies.

Our GOLPH3 Gene Knockout Cell Lines stand out in the marketplace due to their high specificity, proven reliability, and comprehensive validation, which provide researchers with confidence in their experimental results. Unlike alternative models that may produce non-specific or variable knockout effects, our cell lines assure precise gene disruption, significantly improving the reproducibility of research findings.

For researchers, clinicians, and pharmaceutical developers, the value of GOLPH3 Gene Knockout Cell Lines cannot be understated. They represent a critical step in the advancement of biological research, driving innovative discoveries and fostering the development of effective therapies. Our company specializes in providing high-quality genetic models, backed by extensive expertise in gene editing methodologies, ensuring that our customers receive only the best tools for their scientific inquiries and clinical advancements.

Please note that all services are for research use only. Not intended for any clinical use.

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