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GOLGB1 Knockout Cell Lines

Gene: GOLGB1

Official Full Name: golgin B1provided by HGNC

Gene Summary: Enables RNA binding activity. Involved in protein localization to pericentriolar material. Located in Golgi apparatus and endoplasmic reticulum-Golgi intermediate compartment. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO37583 GOLGB1 Knockout cell line (HeLa) Human GOLGB1 1:3~1:6 Negative Online Inquiry
KO37584 GOLGB1 Knockout cell line (HCT 116) Human GOLGB1 1:2~1:4 Negative Online Inquiry
KO37585 GOLGB1 Knockout cell line (HEK293) Human GOLGB1 1:3~1:6 Negative Online Inquiry
KO37586 GOLGB1 Knockout cell line (A549) Human GOLGB1 1:3~1:4 Negative Online Inquiry

Background

GOLGB1 Gene Knockout Cell Lines are genetically modified cell lines in which the GOLGB1 gene has been selectively disrupted, allowing researchers to study the functional consequences of this gene's absence on cellular processes. GOLGB1 encodes the golgin-160 protein, which plays a crucial role in maintaining Golgi apparatus structure and function, as well as in vesicle transport and cellular signaling mechanisms.

These knockout cell lines demonstrate altered cellular behaviors by providing insights into the mechanisms underlying Golgi-related functions, such as protein glycosylation, lipid transport, and cell division. The methodology behind the creation of these cell lines typically involves CRISPR-Cas9 gene editing technology, ensuring precise and reliable gene targeting. Researchers can utilize these tools to dissect the pathways influenced by GOLGB1 and to explore its implications in diseases such as cancer, neurodegenerative disorders, and infectious diseases.

The scientific importance of GOLGB1 Gene Knockout Cell Lines is evident in their utility for transduction and functional studies; they serve as invaluable models for understanding Golgi dynamics and cellular pathology. Compared to traditional methods of studying gene function, these knockout lines offer a more robust and flexible approach, enabling high-throughput screening and reproducibility across experiments.

Unique selling points of our GOLGB1 Gene Knockout Cell Lines include their specificity, ease of use in various experimental setups, and superior adaptability for gene function studies, providing researchers with a reliable platform to generate novel insights. The ability to effectively explore GOLGB1-related pathways without the confounding effects of functional redundancy observed in whole-organism studies significantly enhances research outcomes.

Our company specializes in producing high-quality genetic models and tools tailored to the needs of researchers and clinicians. By investing in our GOLGB1 Gene Knockout Cell Lines, users gain access to expertly crafted resources that can accelerate their investigations into fundamental biological processes and therapeutic strategies.

Please note that all services are for research use only. Not intended for any clinical use.

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