Gene: GNG7
Official Full Name: G protein subunit gamma 7provided by HGNC
Gene Summary: Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway and regulation of adenylate cyclase activity. Predicted to act upstream of or within behavioral fear response; locomotory behavior; and receptor guanylyl cyclase signaling pathway. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO09022 | GNG7 Knockout cell line (HCT 116) | Human | GNG7 | 1:2~1:4 | Negative | Online Inquiry |
KO09023 | GNG7 Knockout cell line (HEK293) | Human | GNG7 | 1:3~1:6 | Negative | Online Inquiry |
GNG7 Gene Knockout Cell Lines are genetically modified cells developed to specifically inactivate the GNG7 gene, which encodes the gamma subunit of heterotrimeric G-proteins. This product enables researchers to study the role of GNG7 in various physiological and pathological processes, making it a critical tool in cell biology and pharmacology.
The GNG7 knockout mechanism utilizes CRISPR/Cas9 technology to create precise deletions in the GNG7 gene. By eliminating this gene, these cell lines allow for the observation of downstream signaling pathways influenced by G-proteins, particularly those involved in neurotransmission and cellular metabolism. The loss of GNG7 can significantly impact cellular responses, providing insights into how disturbances in G-protein signaling contribute to diseases such as cancer, cardiovascular disorders, and neurodegeneration.
In scientific research and clinical settings, GNG7 knockout cell lines are invaluable for elucidating the biological functions of G-proteins, validating drug targets, and screening for potential therapeutic agents. Their ability to provide a controlled environment for studying G-protein coupled receptor signaling makes them a superior choice for experimental designs focused on translational research.
Compared to alternative methods such as RNA interference or pharmacological inhibition, GNG7 knockout cell lines offer a more robust and permanent solution for gene inactivation, leading to clearer insights into the gene's function without the transient nature of knockdown techniques. This feature ensures reproducibility and reliability of results, which is crucial for advancing our understanding of G-protein biology.
Researchers, clinicians, and pharmaceutical scientists will find significant value in utilizing GNG7 Gene Knockout Cell Lines, as they facilitate innovative studies that could lead to breakthroughs in therapeutic strategies. With a deep commitment to genetic modification techniques and extensive product development experience, our company stands at the forefront of providing high-quality research tools tailored to meet the needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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