Gene: GNG4
Official Full Name: G protein subunit gamma 4provided by HGNC
Gene Summary: Predicted to enable G-protein beta-subunit binding activity. Involved in negative regulation of cell growth. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO09024 | GNG4 Knockout cell line (HCT 116) | Human | GNG4 | 1:2~1:4 | Negative | Online Inquiry |
KO09025 | GNG4 Knockout cell line (HEK293) | Human | GNG4 | 1:3~1:6 | Negative | Online Inquiry |
KO09026 | GNG4 Knockout cell line (A549) | Human | GNG4 | 1:3~1:4 | Negative | Online Inquiry |
GNG4 Gene Knockout Cell Lines are sophisticated biological tools designed to facilitate the exploration of the GNG4 gene, which encodes a vital subunit of the heterotrimeric G-protein complex involved in various cellular signaling pathways. These cell lines have undergone precise editing through CRISPR/Cas9 technology to abrogate the expression of the GNG4 gene, thereby providing researchers with a unique environment to study the gene’s functional role and its implications in physiological and pathological processes.
The key function of these knockout cell lines lies in their ability to enable detailed investigations into the downstream effects of GNG4 loss. By characterizing alterations in cellular signaling pathways, including those related to receptor signaling and cellular motility, researchers can dissect the molecular mechanisms underpinning numerous biological responses. This makes GNG4 Gene Knockout Cell Lines an invaluable asset for studying disorders related to G-protein signaling, such as cancer and neurodegenerative diseases.
In terms of scientific importance, these cell lines serve as a critical model for drug discovery and therapeutic development. Their utility extends to high-throughput screening of pharmacological agents targeting G-protein coupled receptors and other signaling components influenced by GNG4. Understanding the effects of GNG4 gene deletion may reveal novel targets and contribute to the advancement of personalized medicine.
Compared to conventional methods that require labor-intensive and time-consuming processes for gene manipulation, the GNG4 Gene Knockout Cell Lines offer a streamlined, consistent approach to gain insights into gene function. Furthermore, our stringent validation processes ensure high specificity and reproducibility, thereby reducing variability in experimental outcomes.
For researchers and clinicians alike, the value of GNG4 Gene Knockout Cell Lines is evident in their capacity to accelerate discovery while providing a robust, reliable platform for experimental investigation. By leveraging these advanced tools, users can heighten their understanding of cellular function, leading to significant breakthroughs in biomedical research.
Our company prides itself on delivering high-quality research tools backed by years of expertise in genetic engineering and cell line development. With a commitment to facilitating cutting-edge research, we ensure that our products meet the highest scientific standards, empowering the next generation of scientific discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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