Gene: GLYCTK
Official Full Name: glycerate kinaseprovided by HGNC
Gene Summary: This locus encodes a member of the glycerate kinase type-2 family. The encoded enzyme catalyzes the phosphorylation of (R)-glycerate and may be involved in serine degradation and fructose metabolism. Decreased activity of the encoded enzyme may be associated with the disease D-glyceric aciduria. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26539 | GLYCTK Knockout cell line (HeLa) | Human | GLYCTK | 1:3~1:6 | Negative | Online Inquiry |
KO26540 | GLYCTK Knockout cell line (HCT 116) | Human | GLYCTK | 1:2~1:4 | Negative | Online Inquiry |
KO26541 | GLYCTK Knockout cell line (HEK293) | Human | GLYCTK | 1:3~1:6 | Negative | Online Inquiry |
KO26542 | GLYCTK Knockout cell line (A549) | Human | GLYCTK | 1:3~1:4 | Negative | Online Inquiry |
GLYCTK Gene Knockout Cell Lines are precisely engineered cell lines in which the glyoxalase pathway gene, GLYCTK, has been disrupted or "knocked out." This state allows for comprehensive investigation into the physiological impacts of GLYCTK activity, particularly its role in metabolic processes associated with reactive aldehyde detoxification. By utilizing CRISPR-Cas9 technology, our GLYCTK knockout cell lines offer reproducible and reliable models for researchers seeking to examine how modulation of this gene affects cellular response to oxidative stress and contributes to various disease states, including cancer and metabolic disorders.
These cell lines function by providing a controlled environment in which researchers can analyze the cellular phenotypes resulting from the absence of GLYCTK. Researchers can assess changes in metabolic flux, cellular viability, and signal transduction pathways relating to oxidative stress management. The scientific importance of these cell lines lies not only in their ability to elucidate the biological functions of GLYCTK but also in their utility in drug discovery initiatives, where targeted interventions can be explored in a relevant context.
Compared to native cell lines, GLYCTK Gene Knockout Cell Lines afford unique advantages including enhanced specificity in results due to the targeted gene modification, as well as a cohesive platform for high-throughput screening applications. Moreover, they eliminate the confounding variables associated with genetic heterogeneity present in wild-type cells, allowing for clearer interpretations of experimental data.
For researchers and clinicians, these knockout cell lines represent an invaluable resource for advancing knowledge of metabolic pathways and developing novel therapeutic strategies. Our commitment to delivering high-quality, precise biological products ensures that users receive exceptional tools to drive their research forward with confidence.
At our company, we specialize in providing state-of-the-art genetic tools and models that empower scientists to tackle tough questions in biology, making us a trusted partner in the quest for scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.