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GLTP Knockout Cell Lines

Gene: GLTP

Official Full Name: glycolipid transfer proteinprovided by HGNC

Gene Summary: The protein encoded by this gene is similar to bovine and porcine proteins which accelerate transfer of certain glycosphingolipids and glyceroglycolipids between membranes. It is thought to be a cytoplasmic protein. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22842 GLTP Knockout cell line (HeLa) Human GLTP 1:3~1:6 Negative Online Inquiry
KO22843 GLTP Knockout cell line (HCT 116) Human GLTP 1:2~1:4 Negative Online Inquiry
KO22844 GLTP Knockout cell line (HEK293) Human GLTP 1:3~1:6 Negative Online Inquiry
KO22845 GLTP Knockout cell line (A549) Human GLTP 1:3~1:4 Negative Online Inquiry

Background

GLTP Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the expression of the GLTP (glycolipid transfer protein) gene. This innovation allows researchers to investigate the role of GLTP in various biological processes, including lipid metabolism, membrane dynamics, and cellular signaling pathways. By employing CRISPR-Cas9 or other genomic editing technologies, these cell lines serve as invaluable tools for elucidating the physiological significance of GLTP in both health and disease states.

The key function of GLTP is its involvement in the transport of glycolipids between membranes, which plays a critical role in maintaining cellular lipid homeostasis and facilitating signal transduction. The absence of GLTP in these knockout cell lines enables researchers to dissect the genetic and molecular mechanisms underlying diseases associated with glycolipid metabolism, such as certain neurodegenerative disorders and metabolic syndromes. This research can lead to a better understanding of disease pathology and the development of potential therapeutic strategies.

Scientifically, the GLTP Gene Knockout Cell Lines have numerous applications in both basic and applied research settings. They can be utilized for high-throughput screening of small molecules that modulate lipid transfer processes, providing insights into novel therapeutic targets. Additionally, these cell lines are crucial for studying the interactions of glycolipids with proteins involved in membrane trafficking and signaling.

What sets GLTP Gene Knockout Cell Lines apart from alternative products on the market is their unparalleled specificity and validated performance in various assays. These cell lines have been rigorously characterized to ensure reproducibility and reliability in experimental results. Furthermore, they come with comprehensive documentation and customer support from our dedicated team, ensuring that researchers have the resources needed to maximize their study's impact.

The value of GLTP Gene Knockout Cell Lines lies in their ability to enhance our understanding of lipid-related cellular processes, thereby driving forward both fundamental and translational research. Our company specializes in providing high-quality biological products, underscored by our commitment to advancing scientific inquiry and discovery. With our expertise and innovative products, we aim to empower researchers and clinicians alike to address the challenges in lipid biology and beyond.

Please note that all services are for research use only. Not intended for any clinical use.

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