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GLP2R Knockout Cell Lines

Gene: GLP2R

Official Full Name: glucagon like peptide 2 receptorprovided by HGNC

Gene Summary: This gene encodes a G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. [provided by RefSeq, Dec 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05467 GLP2R Knockout cell line (HeLa) Human GLP2R 1:3~1:6 Negative Online Inquiry
KO05468 GLP2R Knockout cell line (A549) Human GLP2R 1:3~1:4 Negative Online Inquiry

Background

GLP2R Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the expression of the glucagon-like peptide 2 receptor (GLP2R). This innovative product serves as a powerful tool for researchers aiming to investigate the biological roles and signaling pathways mediated by GLP2R, a receptor implicated in various physiological processes such as gut function, glucose metabolism, and neural signaling.

The primary function of the GLP2R Gene Knockout Cell Lines is to enable scientists to explore the absence of GLP2R signaling in a controlled environment. By utilizing CRISPR-Cas9 technology or similar gene-editing methods, these cell lines create a robust model for studying the downstream effects of GLP2R deletion. This allows for a clearer understanding of how GLP2R influences cellular responses to peptide hormones, thereby offering insights into its potential role in various disease states, including metabolic disorders and gastrointestinal diseases.

In scientific research and clinical settings, these knockout cell lines hold substantial value. They provide researchers with an invaluable resource for drug discovery and biomarker identification, particularly for conditions related to digestive health and thyroid hormone interactions. Furthermore, the ability to study specific receptor interactions in a controlled setting can lead to breakthroughs in targeted therapies.

What sets our GLP2R Gene Knockout Cell Lines apart from alternatives is the guarantee of high fidelity in gene editing, along with detailed validation of knockout efficacy. Our cell lines undergo rigorous quality control processes, ensuring that they maintain stability and reproducibility across experiments. Additionally, we offer comprehensive support, including experimental protocols and troubleshooting resources, making it easier for researchers to integrate these cell lines into their studies.

In summary, our GLP2R Gene Knockout Cell Lines are an essential addition to the toolkit of modern biological research, fostering advancements in the understanding of gut-brain interactions and metabolic regulation. Backed by years of expertise and a commitment to scientific excellence, our company is dedicated to supporting the research community with high-quality biological products that drive innovation and discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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