Gene: GLOD4
Official Full Name: glyoxalase domain containing 4provided by HGNC
Gene Summary: Enables cadherin binding activity. Located in extracellular exosome and mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23172 | GLOD4 Knockout cell line (HeLa) | Human | GLOD4 | 1:3~1:6 | Negative | Online Inquiry |
KO23173 | GLOD4 Knockout cell line (HCT 116) | Human | GLOD4 | 1:2~1:4 | Negative | Online Inquiry |
KO23174 | GLOD4 Knockout cell line (HEK293) | Human | GLOD4 | 1:3~1:6 | Negative | Online Inquiry |
KO23175 | GLOD4 Knockout cell line (A549) | Human | GLOD4 | 1:3~1:4 | Negative | Online Inquiry |
GLOD4 Gene Knockout Cell Lines are genetically engineered cell lines that have had the GLOD4 gene functionally disrupted or "knocked out." This process allows researchers to study the biological roles of the GLOD4 gene, which is implicated in various cellular processes such as oxidative stress responses and metabolic regulation. By utilizing CRISPR/Cas9 or similar gene-editing technologies, these cell lines provide a powerful means to elucidate the functional implications of GLOD4 in health and disease.
The primary mechanism of action for GLOD4 gene knockout involves the targeted modification of the genomic DNA of the cell line. By creating deletion mutations or insertions that lead to a loss of GLOD4 expression, researchers can observe the resulting phenotypic changes, enabling investigations into the gene's contribution to cellular pathways, disease models, and potential therapeutic targets. This knockout model is particularly valuable in studies concerning cancer biology, neurodegeneration, and metabolic disorders.
Scientific applications are vast and multifaceted, particularly in the realms of molecular biology and pharmacology. Researchers can use GLOD4 knockout cell lines to understand the gene's role in drug responses, cellular signaling, and stress resistance, which holds implications for the development of novel therapeutic strategies in clinical settings.
What distinguishes GLOD4 Gene Knockout Cell Lines from their alternatives is their precision and reliability. Unlike broad-spectrum treatments or non-specific inhibitors, these knockout models offer a clear genetic deletion that allows for unequivocal analysis of downstream effects. This specificity not only enhances data reproducibility but also supports regulatory compliance and rigorous scientific inquiry.
For researchers and clinicians, the ability to investigate molecular mechanisms with high fidelity translates into more robust research outcomes and a deeper understanding of disease pathology. Our company, leveraging years of expertise in genetic manipulation technologies and a commitment to quality control, provides high-quality GLOD4 Gene Knockout Cell Lines, ensuring that your research can proceed with confidence and clarity.
Please note that all services are for research use only. Not intended for any clinical use.
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