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GLB1L Knockout Cell Lines

Gene: GLB1L

Official Full Name: galactosidase beta 1 likeprovided by HGNC

Gene Summary: Predicted to enable beta-galactosidase activity. Predicted to be involved in galactose catabolic process. Predicted to be located in extracellular region. Predicted to be active in vacuole. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17369 GLB1L Knockout cell line (HeLa) Human GLB1L 1:3~1:6 Negative Online Inquiry
KO17370 GLB1L Knockout cell line (HCT 116) Human GLB1L 1:2~1:4 Negative Online Inquiry
KO17371 GLB1L Knockout cell line (HEK293) Human GLB1L 1:3~1:6 Negative Online Inquiry
KO17372 GLB1L Knockout cell line (A549) Human GLB1L 1:3~1:4 Negative Online Inquiry

Background

GLB1L Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the GLB1L gene, which is implicated in various biological processes including lysosomal metabolism and glycoprotein turnover. These knockout cell lines are generated using CRISPR/Cas9 technology to ensure precise and efficient gene disruption, providing a powerful tool for studying gene function, pathways, and disease mechanisms.

The primary function of GLB1L Gene Knockout Cell Lines is to enable researchers to investigate the role of GLB1L in cellular physiology and pathology. By eliminating GLB1L expression, these cell lines facilitate the assessment of downstream signaling pathways and metabolic changes that may occur as a result of disrupted gene activity. Furthermore, they allow researchers to evaluate the effects of GLB1L deficiency on cellular responses to stress, pharmacological agents, and disease models, fostering a deeper understanding of the gene's role in both normal physiology and pathological conditions.

The scientific importance of GLB1L Knockout Cell Lines is particularly evident in research areas such as cancer biology, neurodegenerative diseases, and metabolic disorders. By providing a model to study gene function, these cell lines can help to identify potential therapeutic targets and biomarkers while also validating drug efficacy in genetic contexts that mirror human disease.

Compared to traditional cell lines, the use of knockout cell lines offers specific advantages, such as the ability to draw more relevant conclusions from experiments by mimicking genetic scenarios found in vivo. This is especially crucial in studying gene-dependent mechanisms, as it eliminates the confounding effects that residual gene expression might pose.

For researchers and clinicians, GLB1L Gene Knockout Cell Lines present a valuable asset in the quest for novel insights into genetic contributions to disease and treatment responses. They are designed to aid in the rapid advancement of research projects aiming to elucidate the complexities of gene functions.

Our company is renowned for its expertise in genetic engineering and the development of cutting-edge biological products. We are committed to providing high-quality biological models that support scientific discovery and innovation in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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