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GK3 Knockout Cell Lines

Gene: GK3

Official Full Name: glycerol kinase 3provided by HGNC

Gene Summary: Predicted to enable glycerol kinase activity. Predicted to be involved in glycerol metabolic process; glycerol-3-phosphate biosynthetic process; and triglyceride metabolic process. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17374 GK3 Knockout cell line (HeLa) Human GK3 1:3~1:6 Negative Online Inquiry
KO17375 GK3 Knockout cell line (HCT 116) Human GK3 1:2~1:4 Negative Online Inquiry
KO17376 GK3 Knockout cell line (HEK293) Human GK3 1:3~1:6 Negative Online Inquiry
KO17377 GK3 Knockout cell line (A549) Human GK3 1:3~1:4 Negative Online Inquiry

Background

GK3 Gene Knockout Cell Lines are a specialized collection of genetically modified cell lines, specifically designed to facilitate the functional study of gene function through targeted gene disruption. By employing cutting-edge CRISPR/Cas9 technology, GK3 Cell Lines permit the precise knockout of specific genes, enabling researchers to investigate the phenotypic impacts of gene loss in a controlled environment.

The primary mechanism underlying GK3 Cell Lines is the introduction of double-strand breaks in the targeted gene loci, which are then disrupted through the cellular repair processes, leading to targeted mutations. This allows for the exploration of loss-of-function effects in various pathways and diseases, making these cell lines invaluable in both basic and translational research settings.

Scientifically, GK3 Gene Knockout Cell Lines have significant applications in elucidating gene-function relationships, validating therapeutic targets, and understanding disease mechanisms at the cellular level. Their versatility allows for experimentation across a spectrum of fields, including oncology, neurobiology, and developmental biology, providing vital insights that can contribute to innovative treatment strategies.

Compared to traditional methods of gene silencing, such as RNA interference, GK3 Cell Lines offer more durable and specific gene disruptions without the off-target effects that often complicate therapeutic approaches. This robustness makes them an attractive option for researchers looking for reliable and reproducible models for comprehensive screening and functional studies.

For researchers and clinicians poised to expand their understanding of gene function and its implications in health and disease, GK3 Gene Knockout Cell Lines represent a powerful tool. Their ability to enhance experimental rigor and provide clear insights into gene behavior makes them a valuable investment for any laboratory focused on cutting-edge biological research.

At [Your Company Name], we are committed to advancing scientific discovery by providing high-quality biological products backed by extensive expertise and research support, ensuring that our customers have access to the best tools for their work.

Please note that all services are for research use only. Not intended for any clinical use.

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