Gene: GIPC1
Official Full Name: GIPC PDZ domain containing family member 1provided by HGNC
Gene Summary: GIPC1 is a scaffolding protein that regulates cell surface receptor expression and trafficking (Lee et al., 2008 [PubMed 18775991]).[supplied by OMIM, Apr 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO06552 | GIPC1 Knockout cell line (HeLa) | Human | GIPC1 | 1:3~1:6 | Negative | Online Inquiry |
KO06553 | GIPC1 Knockout cell line (HCT 116) | Human | GIPC1 | 1:2~1:4 | Negative | Online Inquiry |
KO06554 | GIPC1 Knockout cell line (HEK293) | Human | GIPC1 | 1:3~1:6 | Negative | Online Inquiry |
KO06555 | GIPC1 Knockout cell line (A549) | Human | GIPC1 | 1:3~1:4 | Negative | Online Inquiry |
GIPC1 Gene Knockout Cell Lines are genetically modified cell lines developed to specifically lack the expression of the GIPC1 gene, which encodes a protein involved in various cellular processes, including signal transduction, cellular growth, and differentiation. These cell lines serve as vital tools for researchers aiming to investigate the biological roles of GIPC1, its contribution to disease mechanisms, and the signaling pathways it influences.
The primary mechanism of these knockout cell lines involves the targeted disruption of the GIPC1 gene through advanced gene editing techniques such as CRISPR-Cas9. By eliminating the expression of GIPC1, these cell lines allow for the assessment of functional changes in biological processes, enabling scientists to elucidate both direct and indirect pathways influenced by GIPC1. This approach is especially critical in studies related to cancer, neurological disorders, and other diseases associated with aberrant cell signaling and growth.
The scientific importance of GIPC1 Gene Knockout Cell Lines is profound, offering numerous applications in both basic and clinical research. They serve as a model for studying cancer progression and metastasis, investigating drug responses, and elucidating cellular mechanisms underpinning various pathologies. Their utility in screening therapeutic agents targeting GIPC1-associated pathways positions them as pivotal assets for drug discovery and development.
Compared to conventional cell line models, GIPC1 knockout lines provide a unique vantage point for examining the specific functional contributions of GIPC1 without interference from wild-type gene products. This specificity enhances the reliability of experimental outcomes, thereby yielding more precise and relevant data.
For researchers and clinicians, these cell lines offer unparalleled value by enabling high-throughput screening, facilitating mechanistic studies, and potentially leading to novel therapeutic strategies. Their role in advancing our understanding of complex biological systems is unmatched, contributing significantly to the field of molecular biology.
Our company prides itself on its expertise in providing high-quality genetic models that empower the research community. With cutting-edge technology and rigorously validated products, we are committed to supporting scientific inquiry and innovation across diverse biological landscapes.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.