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GID4 Knockout Cell Lines

Gene: GID4

Official Full Name: GID complex subunit 4 homologprovided by HGNC

Gene Summary: The multiprotein Mediator complex is a coactivator required for activation of RNA polymerase II transcription by DNA bound transcription factors. The protein encoded by this gene is thought to be a subunit of the Mediator complex. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17390 GID4 Knockout cell line (HeLa) Human GID4 1:3~1:6 Negative Online Inquiry
KO17391 GID4 Knockout cell line (HCT 116) Human GID4 1:2~1:4 Negative Online Inquiry
KO17392 GID4 Knockout cell line (HEK293) Human GID4 1:3~1:6 Negative Online Inquiry
KO17393 GID4 Knockout cell line (A549) Human GID4 1:3~1:4 Negative Online Inquiry

Background

GID4 Gene Knockout Cell Lines are genetically modified cell lines specifically engineered to lack the GID4 gene, which encodes a protein involved in key cellular processes, including the regulation of gene expression and metabolic pathways. These knockout models serve as critical tools for elucidating the function of GID4 in various biological contexts, allowing researchers to explore alterations in cellular behavior that stem from the absence of this protein.

The primary function of GID4 involves its role as a component of GID complexes that regulate protein turnover and transcriptional responses to cellular stress. This mechanism highlights its importance in maintaining cellular homeostasis, making the GID4 Gene Knockout Cell Lines particularly valuable for studies on metabolic disorders and cancer research. By analyzing differentiation, proliferation, and stress response in GID4-deficient cells, researchers can gain insights into the pathways influenced by this gene and develop targeted therapies.

Scientifically, these knockout cell lines serve as a robust platform in both research and clinical settings. They facilitate high-throughput screening of potential therapeutic compounds and assist in the development of gene-targeted therapies. Compared to traditional cell line models, the GID4 Gene Knockout Cell Lines offer a level of specificity that allows for more precise investigations into the roles of GID4, enabling a deeper understanding of related diseases.

A significant advantage of these cell lines is their ability to simulate physiological conditions through in vivo-like cellular responses. This is essential for researchers seeking to translate laboratory findings into clinical applications. Our GID4 Gene Knockout Cell Lines provide researchers with a unique and powerful resource that merges practicality with relevance, elevating discovery potential.

At our company, we pride ourselves on offering high-quality, rigorously validated genetic models tailored for advanced research needs. Our expertise in developing and maintaining these knockout lines ensures that your research has the reliable foundation it requires to succeed in the complex world of molecular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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