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GBP2 Knockout Cell Lines

Gene: GBP2

Official Full Name: guanylate binding protein 2provided by HGNC

Gene Summary: This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas. [provided by RefSeq, Jul 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO01853 GBP2 Knockout cell line (HeLa) Human GBP2 1:3~1:6 Negative Online Inquiry
KO01854 GBP2 Knockout cell line (A549) Human GBP2 1:3~1:4 Negative Online Inquiry

Background

GBP2 Gene Knockout Cell Lines are specialized cellular models engineered to target and disrupt the GBP2 gene, which is known to play a crucial role in several biological processes, including immune responses and cell signaling pathways. These knockout cell lines are created using advanced genetic editing technologies, such as CRISPR-Cas9, resulting in precise gene deletion that allows researchers to study the functional consequences of GBP2 loss in various cellular contexts.

The primary mechanism of action involves the complete abrogation of GBP2 expression, leading to alterations in cellular behavior, immune modulation, and response to pathogens. As GBP2 is implicated in inflammation and disease resistance, these cell lines serve as invaluable tools for dissecting the gene’s biological role and its involvement in conditions ranging from autoimmune disorders to infectious diseases.

The scientific importance of GBP2 Gene Knockout Cell Lines is underscored by their versatile applications in both fundamental research and clinical investigations. Researchers can utilize these models to elucidate the pathway interactions of GBP2, develop potential therapeutic strategies, and evaluate drug responses in a controlled environment. Moreover, they provide a powerful platform for the study of gene function in various therapeutic modalities, including gene therapy and personalized medicine.

Compared to traditional cell lines, GBP2 Gene Knockout Cell Lines offer distinct advantages by enabling targeted gene disruption, which provides clearer insights into specific gene functions without the confounding effects of residual gene activity. Their tailored nature enhances the reproducibility of results, making them more reliable for hypothesis testing and experimental validation.

For researchers and clinicians seeking to advance their studies in gene functionality and disease mechanisms, GBP2 Gene Knockout Cell Lines represent a pivotal resource. Their use empowers the scientific community to unlock novel insights into gene regulation and pathology, paving the way for innovative treatments.

Our company specializes in providing cutting-edge biological products that are rigorously validated and tailored to meet the demands of modern research. With a commitment to excellence and a deep understanding of genetic models, we aim to support researchers in their quest for knowledge and breakthroughs in biomedical science.

Please note that all services are for research use only. Not intended for any clinical use.

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