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GBP1 Knockout Cell Lines

Gene: GBP1

Official Full Name: guanylate binding protein 1provided by HGNC

Gene Summary: Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04225 GBP1 Knockout cell line (HeLa) Human GBP1 1:3~1:6 Negative Online Inquiry
KO04226 GBP1 Knockout cell line (A549) Human GBP1 1:3~1:4 Negative Online Inquiry

Background

GBP1 Gene Knockout Cell Lines are genetically modified cellular models designed to facilitate the functional analysis of the GBP1 gene, a crucial component implicated in various immune responses and cellular signaling pathways. By employing CRISPR-Cas9 gene-editing technology, these cell lines have been meticulously engineered to disrupt the GBP1 gene, enabling researchers to study its role in pathophysiological processes such as inflammation, infection, and cancer.

The primary function of the GBP1 Gene Knockout Cell Lines is to serve as a controlled system for dissecting the biological significance of GBP1. By eliminating its expression, researchers can explore how the absence of GBP1 affects cell proliferation, migration, and response to external stimuli, thus providing insights into the underlying mechanisms driving diseases. The cell lines are equipped with robust validation, ensuring the absence of off-target effects, which enhances the reliability of experimental outcomes.

In research and clinical settings, the GBP1 Gene Knockout Cell Lines hold significant potential across diverse applications, including drug discovery, personalized medicine, and the development of targeted therapies. Understanding how the loss of GBP1 function influences disease states allows for the identification of novel biomarkers and therapeutic targets, contributing to the advancement of precision healthcare.

Distinctively, our GBP1 Gene Knockout Cell Lines offer a level of specificity and reproducibility that differentiates them from conventional models. Unlike primary cells, which can show variability due to donor differences, these knockout lines provide a consistent platform for experimentation. Moreover, their ease of use in high-throughput screening settings can expedite research timelines, facilitating faster discoveries.

For researchers and clinicians focused on unraveling the complexities of immune responses or targeting GBP1 in their studies, our cell lines present an invaluable tool. With our commitment to innovation and extensive expertise in cell line development, we ensure that our products meet rigorous scientific standards, empowering our clients to push the boundaries of their research effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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