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GAS2 Knockout Cell Lines

Gene: GAS2

Official Full Name: growth arrest specific 2provided by HGNC

Gene Summary: The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2017]

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Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO37700 GAS2 Knockout cell line (A549) Human GAS2 1:3~1:4 Negative Online Inquiry

Background

GAS2 Gene Knockout Cell Lines are specialized cellular models in which the GAS2 gene, known for its role in cytoskeletal organization and cellular dynamics, has been selectively disrupted. These knockout cell lines allow researchers to investigate the functional implications of GAS2 in various biological processes, including cell proliferation, differentiation, and apoptosis. The precision of the gene knockout is achieved through advanced genome-editing technologies, such as CRISPR-Cas9, ensuring specific and effective gene disruption.

The GAS2 protein, implicated in microfilament organization, plays a critical role in maintaining cell shape and motility. By studying these knockout cell lines, researchers can elucidate the molecular pathways influenced by GAS2 deficiency and its broader implications in cellular responses to stress, signaling, and migration. This cellular model is invaluable in both basic research and translational studies, as it provides insights into the pathological mechanisms of diseases where GAS2 is a contributing factor.

One of the significant advantages of utilizing GAS2 Gene Knockout Cell Lines is their ability to mimic specific disease states, offering a relevant platform for drug discovery and therapeutic evaluations. Unlike traditional methods that may involve less precise manipulation or reliance on overexpression systems, these knockout lines provide a clearer understanding of gene functionality and interaction within complex biological networks.

For researchers and clinicians alike, the GAS2 Gene Knockout Cell Lines represent a powerful tool for advancing knowledge in cell biology and for developing targeted therapeutic strategies. The rigorous validation of these cell lines ensures high reproducibility and reliability in experimental outcomes, making them a trusted choice for both academic and pharmaceutical applications.

Our company prides itself on its commitment to quality and innovation in biological products, providing researchers with the tools they need to make groundbreaking discoveries in the life sciences field.

Please note that all services are for research use only. Not intended for any clinical use.

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