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GARRE1 Knockout Cell Lines

Gene: GARRE1

Official Full Name: granule associated Rac and RHOG effector 1provided by HGNC

Gene Summary: Enables CCR4-NOT complex binding activity and small GTPase binding activity. Involved in Rac protein signal transduction. Located in P-body. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32888 GARRE1 Knockout cell line (HeLa) Human GARRE1 1:3~1:6 Negative Online Inquiry
KO32889 GARRE1 Knockout cell line (HCT 116) Human GARRE1 1:2~1:4 Negative Online Inquiry
KO32890 GARRE1 Knockout cell line (HEK293) Human GARRE1 1:3~1:6 Negative Online Inquiry
KO32891 GARRE1 Knockout cell line (A549) Human GARRE1 1:3~1:4 Negative Online Inquiry

Background

GARRE1 gene knockout cell lines are genetically modified cell lines specifically engineered to lack the GARRE1 gene, which is implicated in various physiological processes and disease mechanisms. These cell lines serve as critical tools in biological research, enabling scientists to elucidate the function of the GARRE1 gene and its downstream effects in cellular contexts.

The primary mechanism of these knockout cell lines is the targeted deletion of the GARRE1 gene, achieved through advanced gene-editing technologies such as CRISPR/Cas9. This technique allows for precise modification of the genome, thereby providing a robust platform to investigate the phenotypic consequences of GARRE1 loss. Researchers can use these cell lines to explore various cellular pathways, including proliferation, apoptosis, and metabolic functions, which are crucial for understanding the role of GARRE1 in health and disease.

The scientific significance of GARRE1 knockout cell lines cannot be overstated. They are instrumental in both fundamental research and translational studies, providing insights that can lead to the development of novel therapeutic strategies. Such applications may include cancer research, where alterations in gene function often contribute to tumorigenesis, as well as studies in developmental biology, where understanding gene function is essential for delineating cellular differentiation and organ development.

What sets GARRE1 gene knockout cell lines apart from alternative methods, such as knockdown techniques, is their complete and stable gene disruption, allowing researchers to obtain clearer and more consistent results. This completeness minimizes potential off-target effects that can obscure the interpretation of data, thereby enhancing the reliability of experimental outcomes.

For researchers and clinicians, the value of GARRE1 gene knockout cell lines lies in their capacity to provide actionable data that drives innovation in research and therapeutic development. With an increasing emphasis on precision medicine, these tools allow for a deeper understanding of genetic contributions to disease, facilitating more effective interventions.

Our company prides itself on its commitment to advancing scientific research through high-quality biological products. We leverage state-of-the-art technologies and rigorous validation processes to ensure that our GARRE1 gene knockout cell lines meet the highest standards of reliability and efficacy, empowering scientists and clinicians to achieve their research goals with confidence.

Please note that all services are for research use only. Not intended for any clinical use.

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