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GANC Knockout Cell Lines

Gene: GANC

Official Full Name: glucosidase alpha, neutral Cprovided by HGNC

Gene Summary: Glycosyl hydrolase enzymes hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. This gene encodes a member of glycosyl hydrolases family 31. This enzyme hydrolyses terminal, non-reducing 1,4-linked alpha-D-glucose residues and releases alpha-D-glucose. This is a key enzyme in glycogen metabolism and its gene localizes to a chromosomal region (15q15) that is associated with susceptibility to diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06633 GANC Knockout cell line (HeLa) Human GANC 1:3~1:6 Negative Online Inquiry
KO06634 GANC Knockout cell line (HCT 116) Human GANC 1:2~1:4 Negative Online Inquiry
KO06635 GANC Knockout cell line (HEK293) Human GANC 1:3~1:6 Negative Online Inquiry
KO06636 GANC Knockout cell line (A549) Human GANC 1:3~1:4 Negative Online Inquiry

Background

GANC Gene Knockout Cell Lines represent a sophisticated tool in the realm of molecular biology, particularly designed for gene function studies and therapeutic research. These cell lines are engineered by targeted gene disruption, enabling researchers to systematically explore the biological roles of specific genes, understand disease mechanisms, and develop new therapeutic strategies.

The core functionality of GANC Gene Knockout Cell Lines lies in their ability to provide a controlled environment where the effects of gene loss can be assessed. Utilizing CRISPR/Cas9 technology or other precise gene-editing techniques, researchers can selectively inactivate genes of interest, observing resultant phenotypic changes, signaling pathway alterations, and shifts in cellular mechanisms. This capability is invaluable for dissecting complex gene interactions and their contributions to cellular behaviors in various biological contexts.

The scientific importance of these knockout cell lines is profound, as they serve as foundational models for both basic research and translational studies. In preclinical settings, they allow for the identification and validation of therapeutic targets, as well as the assessment of drug responses in genetically defined contexts. Their application spans fields such as cancer biology, neurobiology, and regenerative medicine, where understanding gene function is crucial for developing targeted therapies.

Compared to alternative model systems, GANC Gene Knockout Cell Lines offer unparalleled specificity and versatility. Traditional knockout methods can often lead to unpredictable pleiotropic effects or require extensive animal studies, which are time-consuming and ethically challenging. In contrast, these cell lines provide rapid results in a simplified format that can streamline the research process and enhance reproducibility.

For researchers and clinicians seeking to advance their understanding of genetics and disease, GANC Gene Knockout Cell Lines present a powerful option. The ability to investigate gene knockouts in a controlled cellular environment enhances experimental precision and accelerates the discovery pipeline.

Our company's expertise in biotechnological innovations ensures that each GANC Gene Knockout Cell Line is developed with the highest standards of quality and precision, equipping researchers with reliable tools to unlock new biological insights and therapeutic possibilities.

Please note that all services are for research use only. Not intended for any clinical use.

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