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GALNT15 Knockout Cell Lines

Gene: GALNT15

Official Full Name: polypeptide N-acetylgalactosaminyltransferase 15provided by HGNC

Gene Summary: Predicted to enable polypeptide N-acetylgalactosaminyltransferase activity. Predicted to be involved in protein O-linked glycosylation. Located in transport vesicle. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30439 GALNT15 Knockout cell line (HEK293) Human GALNT15 1:3~1:6 Negative Online Inquiry

Background

GALNT15 Gene Knockout Cell Lines represent a cutting-edge tool in genetic research, providing researchers with a robust model to study the functional implications of the GALNT15 gene. GALNT15 encodes a polypeptide N-acetylgalactosaminyltransferase, which is crucial in the glycosylation of proteins and lipids, influencing cell signaling and interactions. By systematically knocking out GALNT15 in designated cell lines, scientists can quantitatively analyze its role in cellular processes such as differentiation, survival, and pathogenesis.

The key function of GALNT15 Gene Knockout Cell Lines lies in their ability to offer insights into the gene's contribution to glycomic changes and their downstream effects on disease states, such as cancer and metabolic disorders. The knockout mechanism utilizes targeted CRISPR/Cas9 technology, allowing highly specific deletions or gene alterations, thus maintaining the integrity of surrounding genomic regions. As a result, researchers can investigate the cellular responses to the absence of GALNT15, elucidating its pathway and interactions with other biomolecules.

The scientific importance of these cell lines is underscored by their applications in drug discovery, biomarker identification, and functional genomics. By providing a clear system to explore the role of GALNT15, researchers can innovate therapeutic strategies that harness glycosylation as a target for intervention. This is particularly relevant in understanding complex diseases that exhibit altered glycoprotein profiles.

Compared to other gene knockout models, GALNT15 cell lines stand out due to their high specificity, ease of use, and availability for various applications, reducing the time and costs associated with developing new models. Furthermore, our cell lines are validated for consistent performance across multiple experimental conditions, ensuring reliable and reproducible results.

In summary, GALNT15 Gene Knockout Cell Lines are invaluable for researchers and clinicians aiming to deepen their understanding of glycosylation and its biological repercussions. Our company, recognized for its expertise in developing precision biological products, is committed to supporting innovative research with high-quality tools optimized for the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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