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GALNT13 Knockout Cell Lines

Gene: GALNT13

Official Full Name: polypeptide N-acetylgalactosaminyltransferase 13provided by HGNC

Gene Summary: The GALNT13 protein is a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAcT; EC 2.4.1.41) family, which initiate O-linked glycosylation of mucins (see MUC3A, MIM 158371) by the initial transfer of N-acetylgalactosamine (GalNAc) with an alpha-linkage to a serine or threonine residue.[supplied by OMIM, Apr 2004]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO01362 GALNT13 Knockout cell line (HeLa) Human GALNT13 1:3~1:6 Negative Online Inquiry
KO04219 GALNT13 Knockout cell line (HEK293) Human GALNT13 1:3~1:6 Negative Online Inquiry
KO04220 GALNT13 Knockout cell line (A549) Human GALNT13 1:3~1:4 Negative Online Inquiry

Background

GALNT13 Gene Knockout Cell Lines represent a groundbreaking innovation in the field of molecular biology that provides researchers with a powerful tool for investigating the functional role of the GALNT13 gene, which encodes for an enzyme involved in O-linked glycosylation. These cell lines are engineered through advanced CRISPR/Cas9 gene-editing technology to create a permanent knockout of the GALNT13 gene, enabling a comprehensive exploration of its biological implications.

The primary function of these knockout cell lines lies in their ability to facilitate studies pertaining to glycosylation processes and their downstream effects on cellular behavior, including cell growth, differentiation, and response to treatment. By removing the expression of GALNT13, researchers can elucidate the gene’s contributions to various biological pathways, particularly in the context of diseases where glycosylation anomalies are implicated, such as cancer and cardiovascular disorders.

The scientific importance of GALNT13 Gene Knockout Cell Lines stems from their application in both research and clinical environments. They allow for the identification of novel therapeutic targets and the development of glycosylation inhibitors. Furthermore, these cell lines serve as reliable models for drug testing and biomarker discovery, offering insights that could lead to tailored treatment strategies.

Unlike alternative methods that may only temporarily silence gene expression, our knockout cell lines provide a stable and reproducible model for long-term studies. This longevity is crucial for experiments that require consistent analysis over multiple generations. Additionally, these products are derived from well-characterized parental cell lines, ensuring high-quality performance and reproducibility in experimental results.

Researchers and clinicians alike will find significant value in the GALNT13 Gene Knockout Cell Lines, as they foster a deeper understanding of glycan biology and its medical implications, ultimately driving forward innovations in therapeutic development. Our company has a commitment to excellence in the production of high-quality biological products, leveraging our extensive expertise and state-of-the-art technologies to meet the diverse needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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