Gene: FZD9
Official Full Name: frizzled class receptor 9provided by HGNC
Gene Summary: Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO11749 | FZD9 Knockout cell line (HEK293) | Human | FZD9 | 1:3~1:6 | Negative | Online Inquiry |
KO11750 | FZD9 Knockout cell line (A549) | Human | FZD9 | 1:3~1:4 | Negative | Online Inquiry |
FZD9 Gene Knockout Cell Lines are specialized cell lines created through advanced genetic engineering techniques to delete or disrupt the function of the Frizzled-9 (FZD9) gene. This product serves as a pivotal tool for investigating the role of FZD9 in various biological processes and disease mechanisms, particularly in relation to Wnt signaling pathways, which are critical for cellular communication, differentiation, and development.
The key function of FZD9 Gene Knockout Cell Lines lies in their ability to facilitate the study of the FZD9 gene's contributions to cell signaling and its impact on physiological and pathological states. By knocking out this gene, researchers can analyze the consequent effects on cell behavior, gene expression, and signaling cascades, thereby providing insights into FZD9's role in cancer, neurodegenerative diseases, and tissue regeneration.
Scientifically, these cell lines are invaluable in both research and clinical applications, particularly in drug discovery and development. They provide a reliable model for evaluating the efficacy of therapeutic agents targeting the Wnt signaling pathway, allowing for the identification of potential drug candidates and the exploration of combination therapies.
The advantages of FZD9 Gene Knockout Cell Lines over traditional models include their specificity and reproducibility. Unlike wild-type cells that present a mixed response, these knockout lines offer a uniform genetic background, eliminating variability and facilitating clearer interpretations of experimental results. Additionally, the targeted nature of the knockout allows for precise manipulation of biological pathways, making them an efficient choice for researchers seeking to understand complex interactions.
For researchers, clinicians, and biopharmaceutical companies, investing in FZD9 Gene Knockout Cell Lines provides a significant opportunity to advance understanding of cellular processes and discover novel therapeutics. The ability to precisely investigate the FZD9 gene's role in fundamental biological mechanisms underscores the value of these cell lines in cutting-edge research.
Our company prides itself on delivering high-quality biological products that empower scientists and clinicians to push the boundaries of knowledge. With expertise in genetic engineering and a commitment to innovation, we stand as a trusted partner in the advancement of life sciences research.
Please note that all services are for research use only. Not intended for any clinical use.
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