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FZD5 Knockout Cell Lines

Gene: FZD5

Official Full Name: frizzled class receptor 5provided by HGNC

Gene Summary: Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11762 FZD5 Knockout cell line (HeLa) Human FZD5 1:3~1:6 Negative Online Inquiry
KO11763 FZD5 Knockout cell line (HCT 116) Human FZD5 1:2~1:4 Negative Online Inquiry
KO11764 FZD5 Knockout cell line (HEK293) Human FZD5 1:3~1:6 Negative Online Inquiry
KO11765 FZD5 Knockout cell line (A549) Human FZD5 1:3~1:4 Negative Online Inquiry

Background

FZD5 Gene Knockout Cell Lines are cutting-edge biological tools specifically engineered to facilitate the functional study of the Frizzled-5 (FZD5) gene. FZD5 is a crucial member of the Frizzled family of receptors, which play vital roles in the Wnt signaling pathway that regulates various cellular processes including cell proliferation, differentiation, and migration. By providing a means to study the absence of FZD5 expression, these knockout cell lines allow researchers to investigate its role in physiological and pathological contexts, such as cancer and developmental disorders.

The key function of FZD5 Gene Knockout Cell Lines lies in their ability to modulate Wnt signaling pathways. The knockout of FZD5 enables scientists to elucidate the downstream effects associated with the receptor's signaling mechanisms, thereby providing insights into cellular behavior in various biological systems. This manipulation of gene expression is a powerful mechanism for investigating the complexities of signaling pathways and their impact on cell fate decisions.

In terms of scientific importance, FZD5 Gene Knockout Cell Lines are invaluable in both research and clinical settings. In the field of cancer research, for example, understanding the role of FZD5 can lead to the development of targeted therapies aimed at disrupting aberrant signaling pathways that contribute to tumor growth and metastasis. Moreover, these cell lines can serve as models for drug screening and development, offering a platform to assess the efficacy of novel therapeutic agents.

What distinguishes our FZD5 Gene Knockout Cell Lines from alternatives is their rigorously validated knockout efficiency and the stability of the genetic modification. Our proprietary technology ensures the reliability of experimental results, significantly reducing variability associated with off-target effects that can compromise research outcomes. Additionally, these cell lines can be easily integrated into existing experimental workflows, making them an efficient choice for both new and experienced researchers.

For researchers and clinicians aiming to deepen their understanding of Wnt signaling and its broader implications in biology, FZD5 Gene Knockout Cell Lines represent a valuable resource. Our company takes pride in its commitment to providing high-quality, innovative biological products designed to accelerate scientific discovery. With a track record of excellence in genetic engineering and cell line development, we are dedicated to supporting the research community with tools that foster groundbreaking advancements in life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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