Gene: FXR2
Official Full Name: FMR1 autosomal homolog 2provided by HGNC
Gene Summary: The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X cognitive disability syndrome. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO33168 | FXR2 Knockout cell line (HeLa) | Human | FXR2 | 1:3~1:6 | Negative | Online Inquiry |
KO33169 | FXR2 Knockout cell line (HCT 116) | Human | FXR2 | 1:2~1:4 | Negative | Online Inquiry |
KO33170 | FXR2 Knockout cell line (HEK293) | Human | FXR2 | 1:3~1:6 | Negative | Online Inquiry |
KO33171 | FXR2 Knockout cell line (A549) | Human | FXR2 | 1:3~1:4 | Negative | Online Inquiry |
FXR2 Gene Knockout Cell Lines are genetically engineered cellular models that specifically lack the expression of the FXR2 gene, a crucial component in the regulation of gene expression involved in various cellular pathways. These cell lines enable researchers to study the functional roles of FXR2 in a controlled environment, allowing for the dissection of its contributions to various biological processes such as muscle development, synaptic plasticity, and neurogenesis. The knockout mechanism is typically achieved through CRISPR-Cas9 technology, ensuring precise gene deletion and robust genomic stability in the resultant cell lines.
The key functions of FXR2 are associated with the regulation of mRNA stability and translation, as well as involvement in cellular signaling pathways. By utilizing FXR2 Gene Knockout Cell Lines, researchers can explore the pathological implications of FXR2 dysregulation in various diseases, including muscle disorders and neurodevelopmental conditions. The application of these cell lines extends beyond basic research into clinical settings where understanding the molecular basis of disease can lead to novel therapeutic strategies.
Compared to alternative models, such as wild-type or non-specific knockdown cell lines, FXR2 Gene Knockout Cell Lines provide a more precise fundamental understanding by eliminating the confounding variables associated with partial gene expression. Their use leads to higher reproducibility in experiments and greater certainty in drawing conclusions about FXR2's role in health and disease.
For researchers and clinicians, these knockout cell lines are invaluable tools that empower experimental design, facilitate the exploration of therapeutic targets, and enhance the understanding of FXR2-related disorders. By purchasing FXR2 Gene Knockout Cell Lines, users gain access to an advanced research platform backed by our company’s commitment to providing high-quality biological products rooted in extensive expertise in cellular genetics and molecular biology.
Our organization specializes in the development and production of precision gene-edited cell lines, ensuring our customers receive innovative solutions that drive scientific discovery and advancement in genomics.
Please note that all services are for research use only. Not intended for any clinical use.
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