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FTSJ1 Knockout Cell Lines

Gene: FTSJ1

Official Full Name: FtsJ RNA 2'-O-methyltransferase 1provided by HGNC

Gene Summary: This gene encodes a member of the methyltransferase superfamily. The encoded protein localizes to the nucleolus, binds to S-adenosylmethionine, and may be involved in the processing and modification of ribosomal RNA. Mutations in this gene are associated with cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28952 FTSJ1 Knockout cell line (HeLa) Human FTSJ1 1:3~1:6 Negative Online Inquiry
KO28953 FTSJ1 Knockout cell line (HCT 116) Human FTSJ1 1:2~1:4 Negative Online Inquiry
KO28954 FTSJ1 Knockout cell line (HEK293) Human FTSJ1 1:3~1:6 Negative Online Inquiry
KO28955 FTSJ1 Knockout cell line (A549) Human FTSJ1 1:3~1:4 Negative Online Inquiry

Background

FTSJ1 Gene Knockout Cell Lines are specialized cellular models created through targeted genome editing techniques to eliminate the expression of the FTSJ1 gene. This gene encodes a methyltransferase involved in the processing of ribosomal RNA and is crucial for essential cellular functions such as protein synthesis and cellular growth. The precise gene knockout method enables researchers to elucidate the biological roles of FTSJ1, allowing for a clearer understanding of its involvement in various cellular pathways and disease mechanisms.

The key mechanism underlying the functionality of the FTSJ1 knockout cell lines hinges on the absence of functional FTSJ1 protein, which affects processes like ribosome biogenesis and potentially leads to altered cellular stress responses. These modifications can provide insights into disorders involving ribosomal dysfunction, including certain cancers and genetic diseases. In research and clinical settings, the ability to manipulate the expression of genes is invaluable; FTSJ1 knockout cell lines can serve as powerful tools for drug discovery, genetic studies, and the development of therapeutic strategies targeting ribosomal RNA processing.

What sets FTSJ1 Gene Knockout Cell Lines apart from alternative models is their specificity and the efficiency of gene deletion, which eliminate off-target effects commonly associated with other gene editing technologies. Additionally, these cell lines can be readily characterized and utilized alongside a variety of assays, making them incredibly versatile for diverse research applications.

Investing in FTSJ1 Gene Knockout Cell Lines is not just about acquiring a product; it's about accessing a unique resource that can significantly enhance your research capabilities. The elimination of the FTSJ1 gene opens new avenues for exploration and discovery in the field of molecular biology, making it an essential tool for researchers and clinicians alike. Our company's expertise in generating high-quality, reliable gene knockout models further underscores our commitment to providing innovative solutions for advancing scientific knowledge and improving human health.

Please note that all services are for research use only. Not intended for any clinical use.

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