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FRS3 Knockout Cell Lines

Gene: FRS3

Official Full Name: fibroblast growth factor receptor substrate 3provided by HGNC

Gene Summary: This gene encodes a substrate for the fibroblast growth factor receptor. The encoded protein is found in the peripheral plasma membrane and links fibroblast growth factor receptor stimulation to activators of Ras. The encoded protein down-regulates extracellular regulated kinase 2 through direct binding. [provided by RefSeq, Jul 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31481 FRS3 Knockout cell line (HeLa) Human FRS3 1:3~1:6 Negative Online Inquiry
KO31482 FRS3 Knockout cell line (HCT 116) Human FRS3 1:2~1:4 Negative Online Inquiry
KO31483 FRS3 Knockout cell line (HEK293) Human FRS3 1:3~1:6 Negative Online Inquiry
KO31484 FRS3 Knockout cell line (A549) Human FRS3 1:3~1:4 Negative Online Inquiry

Background

FRS3 Gene Knockout Cell Lines are genetically modified cellular models specifically designed to study the functional role of the FRS3 gene in various biological processes. These knockout cell lines have been meticulously engineered to disrupt the expression of the FRS3 gene, enabling researchers to assess the downstream effects of its absence and to elucidate its involvement in signaling pathways, cellular growth, and differentiation.

The primary function of FRS3 involves its role as a scaffold protein that interacts with various receptor tyrosine kinases and other signaling molecules, playing a crucial role in mediating signal transduction pathways such as MAPK and PI3K. By utilizing FRS3 Gene Knockout Cell Lines, scientists can explore how the loss of this gene affects cellular behaviors, such as proliferation, survival, and response to external stimuli. This can provide vital insights into disease mechanisms, particularly in cancers and developmental disorders where FRS3 is implicated.

The scientific significance of FRS3 Gene Knockout Cell Lines lies in their potential application across diverse research fields, from cancer biology to neurobiology. In clinical settings, the insights gained from these cell lines can inform therapeutic strategies that target FRS3-related pathways, making them highly relevant for drug discovery and development.

One of the key advantages of using FRS3 Gene Knockout Cell Lines is their specificity and reliability compared to alternative models, such as transient knockdown approaches that may have off-target effects. The stable knockout allows for consistent results in repeated experiments, thus enabling more robust data generation.

Researchers and clinicians will find these cell lines particularly valuable as they provide a powerful tool to dissect the molecular underpinnings of the FRS3 gene in health and disease. By incorporating FRS3 Gene Knockout Cell Lines into their workflows, users can streamline the process of hypothesis testing and accelerate their discoveries in biomedical research.

Our company specializes in the development of high-quality biological products for advanced research applications, ensuring that our offerings meet the stringent needs of the scientific community. With a commitment to innovation and excellence, we are dedicated to empowering researchers with the tools necessary to drive scientific progress.

Please note that all services are for research use only. Not intended for any clinical use.

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