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FRMD8 Knockout Cell Lines

Gene: FRMD8

Official Full Name: FERM domain containing 8provided by HGNC

Gene Summary: Involved in positive regulation of tumor necrosis factor production. Located in several cellular components, including centriolar satellite; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09592 FRMD8 Knockout cell line (HeLa) Human FRMD8 1:3~1:6 Negative Online Inquiry
KO09593 FRMD8 Knockout cell line (HCT 116) Human FRMD8 1:2~1:4 Negative Online Inquiry
KO09594 FRMD8 Knockout cell line (HEK293) Human FRMD8 1:3~1:6 Negative Online Inquiry
KO09595 FRMD8 Knockout cell line (A549) Human FRMD8 1:3~1:4 Negative Online Inquiry

Background

FRMD8 Gene Knockout Cell Lines are specialized cellular models engineered to disrupt the expression of the FRMD8 gene, which encodes for the FERM domain-containing protein 8, involved in various regulatory functions in cell signaling and structure. These knockout cell lines are invaluable tools for researchers aiming to understand the role of FRMD8 in cellular processes, including those influencing development, differentiation, and disease pathology, particularly in cancers and neurodegenerative disorders.

The key mechanism of action for these cell lines involves gene editing techniques such as CRISPR-Cas9 or homologous recombination to effectively ablate the FRMD8 gene. By doing so, researchers can observe the resultant phenotypic changes and alterations in cellular pathways, providing insights into gene function and the molecular underpinnings of diseases in which FRMD8 is implicated.

Scientifically, the FRMD8 Gene Knockout Cell Lines hold significant importance as they facilitate the investigation into gene function and serve as platforms for drug discovery and validation. In clinical settings, understanding the pathways influenced by FRMD8 may lead to the development of novel therapeutic strategies. Additionally, these cell lines can be utilized in conjunction with high-throughput screening assays to identify compounds that can modulate FRMD8-related pathways.

Compared to alternative models, such as traditional overexpression systems, FRMD8 Gene Knockout Cell Lines provide a more accurate representation of the in vivo conditions. Their specificity enables researchers to study the loss-of-function effects directly, minimizing background noise from other pathways. This precision, coupled with the ease of use in a variety of assays, positions these cell lines as a premier choice for targeted research applications.

For researchers, clinicians, and biotechnology professionals, the FRMD8 Gene Knockout Cell Lines represent a critical asset in investigating gene function and its implications in health and disease. Our company's extensive expertise in cellular engineering and commitment to quality ensures that these cell lines are optimized for reproducibility and efficiency, aiding your research efforts with unparalleled reliability.

Please note that all services are for research use only. Not intended for any clinical use.

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