Gene: FRMD3
Official Full Name: FERM domain containing 3provided by HGNC
Gene Summary: The protein encoded by this gene is a single pass membrane protein primarily found in ovaries. A similar protein in erythrocytes helps determine the shape of red blood cells, but the function of the encoded protein has not been determined. There is some evidence that this is a tumor suppressor gene, and there is also evidence linking defects in this gene to susceptibility to diabetic nephropathy in type 1 diabetes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21009 | FRMD3 Knockout cell line (HeLa) | Human | FRMD3 | 1:3~1:6 | Negative | Online Inquiry |
KO21010 | FRMD3 Knockout cell line (A549) | Human | FRMD3 | 1:3~1:4 | Negative | Online Inquiry |
FRMD3 Gene Knockout Cell Lines are genetically modified cellular models designed to lack functional copies of the FRMD3 gene, which plays a crucial role in cellular signaling pathways and development. These cell lines are engineered through advanced CRISPR-Cas9 gene editing techniques, ensuring precise and effective gene disruption. By creating a knockout of the FRMD3 gene, researchers can investigate the gene's role in various biological processes, including cell adhesion, proliferation, and differentiation.
The key functionalities of FRMD3 Gene Knockout Cell Lines lie in their ability to mimic conditions where FRMD3 is nonfunctional, enabling detailed studies on the impact of this gene's absence. Researchers can use these models to elucidate the underlying mechanisms of diseases linked with FRMD3 dysregulation, including certain cancers and developmental disorders. This kind of analysis is essential for advancing our understanding of pathological conditions and developing targeted therapies.
In the scientific community, these knockout cell lines are invaluable tools for both basic research and translational studies. By facilitating the exploration of gene function and interaction in a controlled environment, they provide critical insights that can drive the discovery of novel therapeutic strategies. Compared to conventional methods that rely on overexpression or knockdown techniques, these knockout models offer a clearer understanding of gene function without the confounding effects of residual activity.
For researchers and clinicians focused on genomic studies and disease modeling, FRMD3 Gene Knockout Cell Lines represent a cutting-edge resource that can significantly enhance experimental outcomes. Their unique ability to provide reliable and reproducible data on genetic contributions to disease makes them a highly sought-after product in laboratories worldwide.
Our company prides itself on its expertise in producing high-quality biological products, operating under rigorous validation protocols to ensure the reliability and integrity of our offerings. By utilizing our FRMD3 Gene Knockout Cell Lines, you equip your research with a powerful tool that increases the potential for breakthroughs in gene function studies and therapeutic applications.
Please note that all services are for research use only. Not intended for any clinical use.
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