Gene: FOXL2
Official Full Name: forkhead box L2provided by HGNC
Gene Summary: This gene encodes a forkhead transcription factor. The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function. Expansion of a polyalanine repeat region and other mutations in this gene are a cause of blepharophimosis syndrome and premature ovarian failure 3. [provided by RefSeq, Jul 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05860 | FOXL2 Knockout cell line (HeLa) | Human | FOXL2 | 1:3~1:6 | Negative | Online Inquiry |
KO05861 | FOXL2 Knockout cell line (A549) | Human | FOXL2 | 1:3~1:4 | Negative | Online Inquiry |
FOXL2 Gene Knockout Cell Lines are genetically engineered cell lines that have been specifically designed to silence the FOXL2 gene, a transcription factor crucial for ovarian development and function. By achieving a knockout of this gene, researchers can elucidate its role in various biological processes, as well as its implications in conditions such as ovarian dysgenesis and certain tumors.
The primary function of FOXL2 Gene Knockout Cell Lines is to provide a reliable model for studying the consequences of FOXL2 loss. These cell lines utilize CRISPR-Cas9 technology, which facilitates precise editing of the genomic DNA, resulting in targeted deletions. As a result, these cell lines can mimic genetic disorders associated with FOXL2 dysfunction, allowing for the exploration of molecular pathways involved in ovarian biology.
In the realm of scientific research and clinical applications, FOXL2 Knockout Cell Lines serve as indispensable tools. They enable researchers to identify downstream effects of FOXL2 deletion on signaling pathways and gene expression, contributing to a deeper understanding of reproductive health and associated pathologies. Additionally, these cell lines can aid in drug discovery efforts aimed at cancer treatment by allowing for the high-throughput screening of therapeutic compounds.
Compared to traditional knockout methods, FOXL2 Gene Knockout Cell Lines offer several advantages, including high efficiency, reduced off-target effects, and the ability to generate clones that are uniform in their genetic alterations. These features translate to more reliable and reproducible experimental outcomes, elevating the quality of research conducted using these models.
For researchers and clinicians, the value of FOXL2 Gene Knockout Cell Lines lies in their potential to uncover new insights into female reproductive development and associated diseases, ultimately leading to enhanced diagnostic and therapeutic strategies. Our company specializes in delivering high-quality, state-of-the-art biological products, leveraging our expertise in genetic engineering to support advances in biomedical research and clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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