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FOXI3 Knockout Cell Lines

Gene: FOXI3

Official Full Name: forkhead box I3provided by HGNC

Gene Summary: Enables DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in pharyngeal system development. Is active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09851 FOXI3 Knockout cell line (HEK293) Human FOXI3 1:3~1:6 Negative Online Inquiry

Background

FOXI3 Gene Knockout Cell Lines are specialized cell models that serve as pivotal tools in the study of gene function, particularly the FOXI3 transcription factor, which is implicated in various biological processes, including development, cellular differentiation, and tissue homeostasis. These cell lines have been meticulously engineered using CRISPR-Cas9 gene-editing technology to create specific deletions in the FOXI3 gene, thereby enabling researchers to explore the phenotypic consequences of FOXI3 deficiency in a controlled environment.

The core function of FOXI3 Gene Knockout Cell Lines resides in their ability to mimic pathophysiological states by eliminating the expression of FOXI3. This targeted approach allows for detailed investigations into the transcriptional networks regulated by FOXI3 and how its absence affects cellular processes at the molecular level. By providing insight into the roles of FOXI3 in epithelial differentiation and its regulatory effects on other key genes, these cell lines are invaluable for advancing our understanding of developmental biology and disease mechanisms.

From a scientific standpoint, FOXI3 Gene Knockout Cell Lines are instrumental in research focused on congenital disorders, regenerative medicine, and cancer biology. Their applications extend to drug discovery, where understanding the role of FOXI3 can lead to novel therapeutic strategies for diseases that involve aberrant cell signaling and development.

What sets FOXI3 Gene Knockout Cell Lines apart from traditional cell models is their specificity and reliability in research. Unlike conventional knockdown approaches, which may leave residual gene function intact, these knockout lines ensure a complete absence of the target gene, providing more definitive results. Moreover, each batch is rigorously validated for gene editing efficiency and phenotypic characterization, ensuring the integrity and reproducibility of experimental outcomes.

Researchers and clinicians seeking to investigate the contributions of FOXI3 will find immense value in these cell lines, as they facilitate high-throughput screening and mechanistic studies that could lead to groundbreaking discoveries. The ability to rigorously manipulate genetic pathways makes them a critical resource for those at the forefront of biomedical research.

Our company prides itself on delivering cutting-edge biological products that empower scientific inquiry. With a focus on innovation and quality, we are committed to providing researchers with essential tools like the FOXI3 Gene Knockout Cell Lines, fostering advancements in health and disease understanding.

Please note that all services are for research use only. Not intended for any clinical use.

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