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FOXB1 Knockout Cell Lines

Gene: FOXB1

Official Full Name: forkhead box B1provided by HGNC

Gene Summary: Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in several processes, including mammary gland development; nervous system development; and visual learning. Predicted to be located in chromatin and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27910 FOXB1 Knockout cell line (HEK293) Human FOXB1 1:3~1:6 Negative Online Inquiry

Background

FOXB1 Gene Knockout Cell Lines are highly specialized biological tools designed to facilitate the study of the FOXB1 gene's function and its associated pathways in various cellular contexts. These cell lines have been engineered through precise gene editing techniques, such as CRISPR-Cas9, to effectively disrupt the expression of the FOXB1 gene, allowing researchers to investigate its role in cellular processes such as differentiation, proliferation, and apoptosis.

The central mechanism of FOXB1 gene knockout utilizes targeted genome editing to induce double-strand breaks at specific loci, which, when repaired by the cell, leads to the introduction of mutations that prevent the synthesis of functional FOXB1 protein. By employing these cell lines, researchers can obtain insights into the biological implications of FOXB1 disruption, explore its involvement in developmental biology, and assess its potential links to various diseases, including cancer.

From a scientific perspective, the FOXB1 gene is crucial for understanding various regulatory mechanisms that govern normal and pathological cellular functions. The use of FOXB1 knockout cell lines in research settings is essential for elucidating its contributions to oncogenic pathways, thereby providing a platform for developing targeted therapies and enhancing precision medicine approaches.

What sets these FOXB1 Gene Knockout Cell Lines apart from alternative products is their high specificity and reliability, which are validated through extensive characterization. Additionally, the user-friendly protocols for cell line handling and maintenance ensure reproducibility in experimental outcomes, granting researchers confidence in their results.

For researchers and clinicians looking to deepen their understanding of gene function or to explore disease mechanisms, these knockout cell lines represent an invaluable resource. Their ability to model gene deficiency closely mirrors in-vivo conditions, thus bridging the gap between basic research and translational applications.

Our company, with a proven track record in genetic engineering and molecular biology, provides high-quality, rigorously tested FOXB1 Gene Knockout Cell Lines, backed by expert support and comprehensive documentation to aid researchers at every stage of their projects.

Please note that all services are for research use only. Not intended for any clinical use.

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