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FMNL1 Knockout Cell Lines

Gene: FMNL1

Official Full Name: formin like 1provided by HGNC

Gene Summary: This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05244 FMNL1 Knockout cell line (HeLa) Human FMNL1 1:3~1:6 Negative Online Inquiry
KO05245 FMNL1 Knockout cell line (HCT 116) Human FMNL1 1:2~1:4 Negative Online Inquiry
KO05246 FMNL1 Knockout cell line (HEK293) Human FMNL1 1:3~1:6 Negative Online Inquiry
KO05247 FMNL1 Knockout cell line (A549) Human FMNL1 1:3~1:4 Negative Online Inquiry

Background

FMNL1 Gene Knockout Cell Lines are engineered cellular models that facilitate the functional study of the FMNL1 gene, which is known to play a critical role in cellular processes such as cytoskeleton organization and cell migration. These knockout cell lines are created through advanced gene-editing techniques, specifically CRISPR/Cas9, ensuring the precise disruption of the FMNL1 gene. This targeted modification allows researchers to investigate the consequences of FMNL1 loss on cellular behavior, facilitating the elucidation of its biological functions and implications in various physiological and pathological states.

The key functions of FMNL1 are linked to its role in the regulation of actin dynamics, which is essential for processes such as cell motility and shape changes. By employing FMNL1 Gene Knockout Cell Lines, researchers can study the subsequent alterations in actin filament organization, cellular adhesion, and the migration capacity of cells. This is invaluable for understanding the mechanisms underlying various diseases, including cancer metastasis and developmental disorders where cell movement is crucial.

The scientific importance of these knockout cell lines is underscored by their applications in both basic research and clinical settings. They provide a robust platform for investigating the pathophysiology of diseases correlated with altered FMNL1 function and may serve as a tool for drug discovery, enabling the testing of therapeutic strategies aimed at modulating FMNL1 activity.

One of the significant advantages of FMNL1 Gene Knockout Cell Lines is their high degree of specificity and reliability compared to traditional gene silencing methods such as RNA interference, which can yield off-target effects. Furthermore, these cell lines are designed to be easy-to-use and offer reproducible results, making them a favorite among researchers who require accurate and efficient experimental outcomes.

These knockout cell lines are invaluable to researchers and clinicians seeking to understand the role of the FMNL1 gene in a variety of biological contexts, aiding in the generation of insights that can translate into novel therapeutic interventions. Our company brings years of expertise in the field of genetic engineering and cell line development, ensuring that our FMNL1 Gene Knockout Cell Lines are of the highest quality and supported with comprehensive user resources to enhance your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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