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FKBP1C Knockout Cell Lines

Gene: FKBP1C

Official Full Name: FKBP prolyl isomerase family member 1Cprovided by HGNC

Gene Summary: Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in negative regulation of activin receptor signaling pathway and negative regulation of transforming growth factor beta receptor signaling pathway. Predicted to be active in sarcoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26382 FKBP1C Knockout cell line (HeLa) Human FKBP1C 1:3~1:6 Negative Online Inquiry
KO26383 FKBP1C Knockout cell line (HCT 116) Human FKBP1C 1:2~1:4 Negative Online Inquiry
KO26384 FKBP1C Knockout cell line (A549) Human FKBP1C 1:3~1:4 Negative Online Inquiry

Background

FKBP1C Gene Knockout Cell Lines are genetically modified cell lines that have undergone precise gene editing to disrupt the FKBP1C gene, which encodes a key immunophilin involved in various cellular processes, including protein folding, trafficking, and signaling. These knockout models are pivotal in studying the functional implications of FKBP1C deletion, particularly in the context of immunological responses and cellular stress mechanisms.

The primary function of FKBP1C Gene Knockout Cell Lines is to facilitate research into the biochemical pathways that rely on FKBP1C. The absence of this gene allows scientists to observe the resultant phenotypic changes and altered signaling pathways, which can yield insights into its role in diseases such as cancer or autoimmune disorders. The methodology used typically includes CRISPR/Cas9 technology or other advanced genome editing techniques, ensuring precise targeting and efficient knockout rates.

These cell lines hold immense scientific importance in both fundamental research and translational studies. They provide invaluable models for drug discovery, particularly in screening small molecules that impact FKBP1C-related pathways, as well as for understanding the mechanisms underlying drug resistance and therapeutic responses.

What sets FKBP1C Gene Knockout Cell Lines apart from alternative models is their specificity and reliability. Unlike transient knockdown approaches, which may lead to off-target effects or temporary results, these knockout lines provide a stable and reproducible platform, allowing for consistent results across experiments. This stability is crucial for generating reliable data in long-term studies and validates more robust conclusions.

For researchers and clinicians, the ability to dissect the intricacies of FKBP1C’s function enhances the potential for developing novel therapeutic strategies and elucidating disease mechanisms. This product empowers users to push the boundaries of current biomedical knowledge and create innovations that translate into clinical applications.

As a leader in the field of genetic modifications, our company prides itself on providing high-quality, rigorously validated cell lines that cater to the evolving needs of the scientific community. By choosing our FKBP1C Gene Knockout Cell Lines, researchers can rely on a product that marries cutting-edge science with exceptional user support, driving discoveries that matter.

Please note that all services are for research use only. Not intended for any clinical use.

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