Gene: FKBP15
Official Full Name: FKBP prolyl isomerase family member 15provided by HGNC
Gene Summary: Predicted to enable actin binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in endocytosis. Located in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29492 | FKBP15 Knockout cell line (HeLa) | Human | FKBP15 | 1:3~1:6 | Negative | Online Inquiry |
KO29493 | FKBP15 Knockout cell line (HCT 116) | Human | FKBP15 | 1:2~1:4 | Negative | Online Inquiry |
KO29494 | FKBP15 Knockout cell line (HEK293) | Human | FKBP15 | 1:3~1:6 | Negative | Online Inquiry |
KO29495 | FKBP15 Knockout cell line (A549) | Human | FKBP15 | 1:3~1:4 | Negative | Online Inquiry |
FKBP15 Gene Knockout Cell Lines are genetically modified mammalian cell lines engineered to lack the expression of the FKBP15 gene. This gene encodes a member of the FK506-binding protein family, which plays a crucial role in various cellular processes, including protein folding, proliferation, and apoptosis. By knocking out FKBP15, these cell lines serve as essential tools for dissecting the gene's function and its downstream effects on cellular mechanisms, ultimately enhancing our understanding of its biological pathways.
The primary functions of FKBP15 involve functioning as a peptidyl-prolyl cis-trans isomerase, which is instrumental in assisting the proper folding of proteins, in addition to having a role in stress response mechanisms. By utilizing these knockout cell lines, researchers can investigate the loss of FKBP15 and evaluate changes in cell growth patterns, stress responses, or protein interactions, paving the way for novel insights in fields such as cancer biology and neurology.
The scientific importance of FKBP15 Gene Knockout Cell Lines extends into both research and clinical applications. They can be employed as model systems for studying the role of FKBP15 in disease pathogenesis, allowing for the exploration of therapeutic targets and the development of potential interventions. These cell lines are particularly valuable for high-throughput screening of compounds that may modulate the effects observed in FKBP15 deficiency.
What sets our FKBP15 Gene Knockout Cell Lines apart from alternatives is their robust validation and the high specificity of the knockout, which ensures minimal off-target effects. These lines are generated using state-of-the-art CRISPR/Cas9 technology, confirming the reliability and reproducibility of experimental results.
For researchers and clinicians, the availability of such engineered cell lines translates into efficient resources for mechanistic studies and drug development. Their unique ability to model gene function loss provides insights that can translate to clinical applications, guiding therapeutic strategies.
At [Your Company Name], we pride ourselves on our commitment to advancing research through high-quality biological products. Our expertise in genetic engineering and our meticulous validation processes ensure that our FKBP15 Gene Knockout Cell Lines meet the rigorous demands of modern biological research, empowering scientists to push the boundaries of discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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