Gene: FIRRM
Official Full Name: FIGNL1 interacting regulator of recombination and mitosisprovided by HGNC
Gene Summary: Enables protein kinase binding activity. Involved in several processes, including chromosome segregation; interstrand cross-link repair; and regulation of protein kinase activity. Located in several cellular components, including kinetochore; midbody; and spindle midzone. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17591 | FIRRM Knockout cell line (HeLa) | Human | FIRRM | 1:3~1:6 | Negative | Online Inquiry |
KO17592 | FIRRM Knockout cell line (HCT 116) | Human | FIRRM | 1:2~1:4 | Negative | Online Inquiry |
KO17593 | FIRRM Knockout cell line (HEK293) | Human | FIRRM | 1:3~1:6 | Negative | Online Inquiry |
KO17594 | FIRRM Knockout cell line (A549) | Human | FIRRM | 1:3~1:4 | Negative | Online Inquiry |
FIRRM Gene Knockout Cell Lines are specialized cellular models engineered to precisely eliminate specific genes of interest, enabling researchers to investigate gene functionality and elucidate cellular pathways. Utilizing advanced CRISPR-Cas9 technology, these cell lines facilitate the creation of knockouts in a range of genomic contexts, thereby allowing for the analysis of gene loss-of-function effects on cellular behavior, signaling pathways, and disease models.
The primary mechanism at play in FIRRM Gene Knockout Cell Lines involves the targeted introduction of double-strand breaks at precise genomic locations, which are subsequently repaired by non-homologous end joining (NHEJ), leading to insertions or deletions that disrupt gene function. This approach provides an effective tool for studying gene roles in developmental processes, disease progression, and therapeutic responses. Importantly, these knockout cell lines can be employed in a wide variety of research applications, including cancer biology, pharmacogenomics, and regenerative medicine.
What sets FIRRM Gene Knockout Cell Lines apart from traditional knockout systems is their versatility, reliability, and user-friendly protocols that ensure researchers can generate consistent and reproducible results. The ability to rapidly create cell lines with specific genetic alterations accelerates the pace of scientific discovery, allowing for streamlined experimental workflows. Furthermore, these cell lines are thoroughly characterized for off-target effects, ensuring the validity and reliability of the experimental results.
For researchers and clinicians aiming to explore gene functionality, FIRRM Gene Knockout Cell Lines represent a breakthrough solution that enhances experimental accuracy and efficiency. By using these cell lines, users can obtain insights that are crucial for developing targeted therapies and understanding complex biological processes.
At FIRRM, our commitment to advancing biological research is reflected in our expertise in gene editing technologies. We provide high-quality products designed to meet the evolving needs of the scientific community, ensuring that you have the tools necessary to drive innovation and discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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