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FEZF1 Knockout Cell Lines

Gene: FEZF1

Official Full Name: FEZ family zinc finger 1provided by HGNC

Gene Summary: This gene encodes a transcriptional repressor that belongs to the zinc finger double domain protein family. The encoded protein is thought to play a role in the embryonic migration of gonadotropin-releasing hormone neurons into the brain. Mutations in this gene are associated with hypogonadotropic hypogonadism-22 with anosmia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

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Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17628 FEZF1 Knockout cell line (HEK293) Human FEZF1 1:3~1:6 Negative Online Inquiry

Background

FEZF1 Gene Knockout Cell Lines are specifically engineered cellular models that lack the expression of the FEZF1 gene, which is critical for various neurological and developmental processes. This gene encodes a zinc finger transcription factor that plays a crucial role in neuronal differentiation and synaptic function. By utilizing precise gene editing techniques, these knockout cell lines allow researchers to explore the functions of the FEZF1 gene under controlled experimental conditions.

The key mechanisms by which these cell lines operate involve the disruption of normal gene function, enabling the assessment of the resulting phenotypic changes, such as alterations in cell behavior, migration patterns, and signaling pathways associated with neural development. Such investigations provide invaluable insights into the gene’s role in diseases, including neurodevelopmental disorders and conditions affecting synaptic plasticity.

In research and clinical settings, FEZF1 Gene Knockout Cell Lines are pivotal for elucidating the molecular mechanisms underpinning several neurological conditions, potentially leading to the development of targeted therapeutic strategies. Their application ranges from basic research aimed at understanding gene function to more translational studies focusing on the paths to novel treatments.

Compared to traditional models, the unique selling point of these knockout cell lines lies in their specificity and precision, providing researchers with clear and reliable data that may not be achievable with alternative models like siRNA knockdowns or pharmacological inhibitors. The clear delineation of gene function offered by these cell lines facilitates accelerated discovery processes and enhances reproducibility in experimental outcomes.

For researchers and clinicians alike, the value of FEZF1 Gene Knockout Cell Lines is profound—they enable an advanced understanding of gene-related mechanisms and their implications for human health. Coupled with our company's robust expertise in genetic engineering and cellular biology, we provide researchers with high-quality, ready-to-use models to exploit for groundbreaking scientific inquiries.

Please note that all services are for research use only. Not intended for any clinical use.

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