Gene: FCMR
Official Full Name: Fc mu receptorprovided by HGNC
Gene Summary: Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM (see MIM 147020) (Kubagawa et al., 2009 [PubMed 19858324]; Shima et al., 2010 [PubMed 20042454]).[supplied by OMIM, Jul 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04765 | FCMR Knockout cell line (HeLa) | Human | FCMR | 1:3~1:6 | Negative | Online Inquiry |
KO04766 | FCMR Knockout cell line (A549) | Human | FCMR | 1:3~1:4 | Negative | Online Inquiry |
FCMR Gene Knockout Cell Lines are specialized cellular models engineered to lack the functional expression of the FCMR (Fc Fragment of IgM Receptor) gene. This innovative product leverages advanced CRISPR/Cas9 genome-editing technologies to create precise genetic modifications, allowing researchers to delineate the role of FCMR in various biological processes, immune responses, and disease mechanisms. By eliminating the FCMR gene, these cell lines serve as essential tools for studying receptor signaling pathways and the associated physiological impacts.
The fundamental mechanism at work involves the targeted disruption of the FCMR gene, which results in the loss of receptor expression. This allows researchers to investigate the functional consequences of FCMR deficiency, particularly its implications in immunological contexts, such as antibody-mediated responses and pathogen recognition. With applications in both fundamental and applied biomedical research, these cell lines provide invaluable insights into therapeutic targets for autoimmune disorders, infectious diseases, and cancer immunotherapy.
The scientific importance of FCMR Gene Knockout Cell Lines is underscored by their versatility in research. They offer a unique opportunity to unravel complex immune signaling cascades and validate potential therapeutic interventions. Compared to traditional knockout models, these engineered cell lines are easier and quicker to scale, ensuring consistency and replicability throughout experimental protocols. Additionally, they eliminate the variability associated with whole-animal models, providing clearer insights into cellular mechanisms.
For researchers and clinicians, the availability of FCMR Gene Knockout Cell Lines signifies a leap forward in experimental biology. They offer the potential for high-throughput screening of drug candidates and biological pathways, facilitating accelerated discovery and development processes. By utilizing these cell lines, users can not only enhance their understanding of the immune system but also pave the way for novel therapeutic strategies.
Our company specializes in the production of high-quality genetic models and biologically relevant tools, backed by a commitment to scientific rigor and innovation. With a wealth of expertise and a portfolio that is continuously evolving, we are dedicated to empowering researchers in their pursuit of groundbreaking discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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