Gene: FBXL19
Official Full Name: F-box and leucine rich repeat protein 19provided by HGNC
Gene Summary: This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein is reported to bind to the transmembrane receptor interleukin 1 receptor-like 1 and regulate its ubiquitination and degradation. This protein has been linked to the regulation of pulmonary inflammation and psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21588 | FBXL19 Knockout cell line (HeLa) | Human | FBXL19 | 1:3~1:6 | Negative | Online Inquiry |
KO21589 | FBXL19 Knockout cell line (HCT 116) | Human | FBXL19 | 1:2~1:4 | Negative | Online Inquiry |
KO21590 | FBXL19 Knockout cell line (HEK293) | Human | FBXL19 | 1:3~1:6 | Negative | Online Inquiry |
KO21591 | FBXL19 Knockout cell line (A549) | Human | FBXL19 | 1:3~1:4 | Negative | Online Inquiry |
FBXL19 Gene Knockout Cell Lines are genetically engineered cellular models that have undergone precise genome editing to disrupt the function of the FBXL19 gene. This innovative product offers researchers a powerful tool for investigating the biological roles of FBXL19 and its implications in various cellular processes, including cell cycle regulation, transcriptional control, and cellular response to environmental stimuli. The knockout mechanism primarily involves the introduction of targeted mutations through CRISPR-Cas9 technology, leading to a non-functional FBXL19 protein.
These cell lines serve as essential models for studying the gene's involvement in diseases such as cancer, neurodevelopmental disorders, and metabolic syndromes. Researchers can utilize these knockout models to dissect the molecular pathways modulated by FBXL19, assess potential therapeutic targets, and evaluate drug responses in a controlled setting. The ability to study gene function in a relevant cellular context enhances the understanding of disease mechanisms and aids in the development of novel therapeutic strategies.
Compared to traditional gene silencing methods, FBXL19 Gene Knockout Cell Lines provide a more stable and permanent solution for gene disruption, yielding consistent results over time. This reliability is crucial for long-term studies and experimentation, making it a preferred choice among researchers seeking reproducibility and precision in gene function studies.
Our company specializes in advanced genetic engineering technology, focusing on the development of high-quality cellular models that assist scientists in their quest for groundbreaking research. By choosing FBXL19 Gene Knockout Cell Lines, users gain access to an expertly designed product that empowers their research, ultimately fostering advancements in health and medicine.
Please note that all services are for research use only. Not intended for any clinical use.
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