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FBXL14 Knockout Cell Lines

Gene: FBXL14

Official Full Name: F-box and leucine rich repeat protein 14provided by HGNC

Gene Summary: Members of the F-box protein family, such as FBXL14, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24090 FBXL14 Knockout cell line (HeLa) Human FBXL14 1:3~1:6 Negative Online Inquiry
KO24091 FBXL14 Knockout cell line (HCT 116) Human FBXL14 1:2~1:4 Negative Online Inquiry
KO24092 FBXL14 Knockout cell line (HEK293) Human FBXL14 1:3~1:6 Negative Online Inquiry
KO24093 FBXL14 Knockout cell line (A549) Human FBXL14 1:3~1:4 Negative Online Inquiry

Background

FBXL14 Gene Knockout Cell Lines are genetically engineered models designed specifically to study the biological functions of the FBXL14 gene, which is implicated in various cellular processes, including cell cycle regulation and protein degradation pathways. These cell lines provide a valuable tool for researchers seeking to unravel the complex interactions and regulatory mechanisms influenced by FBXL14, especially in the context of diseases such as cancer and neurodegenerative disorders.

The core functionality of FBXL14 Gene Knockout Cell Lines lies in their capacity to facilitate the investigation of FBXL14's role by allowing researchers to observe phenotypic changes in the absence of this gene. By employing CRISPR-Cas9 gene editing technology, these knockout lines ensure precise and efficient disruption of the FBXL14 gene, enabling detailed analysis of pathways and molecular networks affected by its loss. This mechanism provides a robust platform for elucidating signaling cascades and identifying potential therapeutic targets.

From a scientific perspective, these cell lines have significant implications in both basic and translational research. They serve as critical models for studying gene function, understanding disease mechanisms, and establishing the roles of FBXL14 in cellular processes. Additionally, the insights gained can aid in the development of targeted therapies, ultimately advancing clinical applications in personalized medicine.

What sets FBXL14 Gene Knockout Cell Lines apart from alternative models is their specificity and reliability. Unlike traditional methods that may result in off-target effects, our gene knockout lines provide a clean and definitive approach, ensuring that researchers can draw accurate conclusions about FBXL14's biological role. Furthermore, these cell lines are extensively characterized and validated, guaranteeing consistency and reproducibility across experiments.

The value of FBXL14 Gene Knockout Cell Lines to researchers and clinicians cannot be overstated. They not only deepen our understanding of fundamental biological processes but also pave the way for innovations in treatment strategies against various diseases. By investing in our quality offerings, users gain access to tools that enhance their research outcomes and contribute to our collective understanding of complex biological systems.

As a leader in the production of high-quality biological research tools, our company is committed to delivering advanced genetic products like the FBXL14 Gene Knockout Cell Lines. With a focus on innovation and scientific excellence, we empower researchers to achieve groundbreaking discoveries and drive the future of medical science.

Please note that all services are for research use only. Not intended for any clinical use.

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