Gene: FBLN2
Official Full Name: fibulin 2provided by HGNC
Gene Summary: This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37910 | FBLN2 Knockout cell line (HeLa) | Human | FBLN2 | 1:3~1:6 | Negative | Online Inquiry |
KO37911 | FBLN2 Knockout cell line (A549) | Human | FBLN2 | 1:3~1:4 | Negative | Online Inquiry |
FBLN2 Gene Knockout Cell Lines are specialized cell lines generated through targeted gene disruption techniques, specifically designed to study the function of the Fibulin-2 (FBLN2) gene. This biological product allows researchers to investigate the role of FBLN2 in various cellular processes, such as extracellular matrix organization, tissue morphogenesis, and fibrosis. By eliminating the FBLN2 gene, these knockout cell lines provide a model to understand the gene's contribution to physiological and pathological conditions, including developmental disorders and cancer.
The functionality of FBLN2 Gene Knockout Cell Lines stems from their precise genetic modification, which enables the observation of compensatory mechanisms and alternative pathways that may compensate for the loss of FBLN2. Researchers can utilize these cell lines in assays to elucidate the roles FBLN2 plays in cellular adhesion, migration, and signaling pathways integral to cellular homeostasis. This mechanistic insight is crucial for advancing knowledge in cell biology and regenerative medicine.
Scientifically, the FBLN2 knockout model holds significant importance in both research and clinical settings. For researchers, these cell lines serve as valuable tools for investigating specific pathways or interactions that may lead to novel therapeutic targets in diseases characterized by altered extracellular matrix composition. Clinicians can leverage findings from such models to inform treatments for conditions linked to aberrant FBLN2 expression.
In comparison to traditional cell lines, which express the FBLN2 gene, our knockout cell lines offer distinct advantages. They provide a controlled environment for dissecting the gene's role, reducing confounding variables associated with gene expression heterogeneity. The precision and reliability of these knockout cell lines set them apart from alternatives, making them an invaluable resource for both fundamental research and translational studies.
For researchers and clinicians alike, the FBLN2 Gene Knockout Cell Lines represent a cutting-edge approach to understanding the complexities of gene function in health and disease. With our commitment to producing high-quality biological products backed by rigorous scientific validation, we ensure that our customers have access to tools that enhance their research capabilities and clinical insights.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.