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FBF1 Knockout Cell Lines

Gene: FBF1

Official Full Name: Fas binding factor 1provided by HGNC

Gene Summary: Involved in apical junction assembly and establishment of epithelial cell polarity. Acts upstream of or within cilium assembly. Located in apical junction complex and cytoskeleton. Part of ciliary transition fiber. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24303 FBF1 Knockout cell line (HeLa) Human FBF1 1:3~1:6 Negative Online Inquiry
KO24304 FBF1 Knockout cell line (HCT 116) Human FBF1 1:2~1:4 Negative Online Inquiry
KO24305 FBF1 Knockout cell line (HEK293) Human FBF1 1:3~1:6 Negative Online Inquiry
KO24306 FBF1 Knockout cell line (A549) Human FBF1 1:3~1:4 Negative Online Inquiry

Background

FBF1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the FBF1 gene, a crucial component implicated in various biological processes, including RNA binding, regulation of gene expression, and developmental signaling pathways. These knockout cell lines serve as powerful tools for researchers studying gene function, cellular mechanisms, and the molecular pathways associated with FBF1. By specifically abrogating the FBF1 gene, scientists can investigate the resulting phenotypic and physiological changes, enabling a deeper understanding of its role in normal cellular processes and disease mechanisms.

The key mechanism by which FBF1 Gene Knockout Cell Lines operates involves targeted genome editing techniques, such as CRISPR/Cas9 methodology, designed to introduce precise mutations that disrupt the functionality of the FBF1 gene. This allows researchers to observe the impact of the absence of FBF1 on cellular proliferation, differentiation, and stress responses in various contexts, including cancer research, regenerative medicine, and developmental biology.

The scientific importance of these knockout cell lines lies in their versatility and potential for application in both basic and translational research. They provide invaluable insights into gene function and can be used to explore therapeutic targets for diseases associated with dysregulated gene expression. Such cell lines are crucial for validating hypotheses, assessing drug responses, and elucidating the molecular mechanisms underlying complex diseases.

Compared to existing alternatives, FBF1 Gene Knockout Cell Lines offer enhanced specificity and reliability. While other models might rely on partial gene inhibition or overexpression approaches, the complete knockout ensures a thorough assessment of gene function without the confounding effects of residual activity. This clarity in experimental outcomes is paramount for rigorous scientific investigation.

For researchers and clinicians, the value of utilizing FBF1 Gene Knockout Cell Lines is significant. They provide a definitive resource for unraveling the complexities of gene interactions and thereby aid in identifying novel biomarkers and therapeutic strategies. As specialists in the field of biological models, our company ensures that these cell lines are rigorously validated, offering a reliable foundation for cutting-edge research and innovation in life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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