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FANK1 Knockout Cell Lines

Gene: FANK1

Official Full Name: fibronectin type III and ankyrin repeat domains 1provided by HGNC

Gene Summary: Involved in regulation of DNA-templated transcription and regulation of apoptotic process. Located in chromatin; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22858 FANK1 Knockout cell line (HeLa) Human FANK1 1:3~1:6 Negative Online Inquiry
KO22859 FANK1 Knockout cell line (HCT 116) Human FANK1 1:2~1:4 Negative Online Inquiry
KO22860 FANK1 Knockout cell line (A549) Human FANK1 1:3~1:4 Negative Online Inquiry

Background

FANK1 Gene Knockout Cell Lines are specifically engineered cell lines that have undergone targeted genetic modification to disrupt the function of the FANK1 gene. This advanced biotechnological tool enables researchers to study the role of FANK1 in various biological processes, particularly its involvement in cellular signaling pathways and tumorigenesis. By creating knockout models, scientists can elucidate the phenotypic consequences of FANK1 loss, providing insights into its potential role as a therapeutic target.

The primary mechanism of the FANK1 Gene Knockout Cell Lines involves CRISPR-Cas9 gene editing technology, which facilitates precise alterations in the genomic DNA. This allows for the complete ablation of the FANK1 gene, leading to reduced protein expression and offering a robust platform for investigating the downstream effects on cellular behavior. By employing these knockout lines, researchers can perform functional assays to assess changes in proliferation, apoptosis, and response to drug treatment, thereby advancing our understanding of the gene's implications in cancer biology and other disease states.

The scientific importance of FANK1 Gene Knockout Cell Lines cannot be overstated, as they are invaluable in basic research and translational applications. In clinical settings, these models can assist in drug discovery processes by identifying how modifications in FANK1 influence therapeutic responses, ultimately paving the way for more effective treatment strategies.

Compared to alternative methods such as siRNA-mediated knockdown or pharmacological inhibitors, FANK1 Gene Knockout Cell Lines offer a more permanent and stable solution for studying the gene’s function. This permanency allows researchers to observe long-term effects on cellular systems, leading to more reliable and reproducible results.

For researchers and clinicians seeking to deepen their understanding of genetic contributions to disease and to refine their investigative capabilities in cell biology, FANK1 Gene Knockout Cell Lines provide unmatched value. These expertly crafted models empower users to drive forward their research objectives efficiently.

Our company, with a strong foundation in genetic engineering and a commitment to innovation, offers a diverse portfolio of biological products, including FANK1 Gene Knockout Cell Lines, to support the scientific community in pushing the boundaries of biological research and therapeutic development.

Please note that all services are for research use only. Not intended for any clinical use.

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