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FAM83D Knockout Cell Lines

Gene: FAM83D

Official Full Name: family with sequence similarity 83 member Dprovided by HGNC

Gene Summary: Enables kinesin binding activity; microtubule binding activity; and protein kinase binding activity. Involved in several processes, including positive regulation of cell cycle G1/S phase transition; protein localization to mitotic spindle; and regulation of intracellular signal transduction. Located in cytosol; intercellular bridge; and mitotic spindle pole. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25702 FAM83D Knockout cell line (HeLa) Human FAM83D 1:3~1:6 Negative Online Inquiry
KO25703 FAM83D Knockout cell line (HCT 116) Human FAM83D 1:2~1:4 Negative Online Inquiry
KO25704 FAM83D Knockout cell line (HEK293) Human FAM83D 1:3~1:6 Negative Online Inquiry
KO25705 FAM83D Knockout cell line (A549) Human FAM83D 1:3~1:4 Negative Online Inquiry

Background

FAM83D Gene Knockout Cell Lines are specialized cell cultures engineered to lack the FAM83D gene, which is implicated in various cellular processes, including cell proliferation and differentiation. By targeting the FAM83D gene through precise CRISPR/Cas9 gene-editing technology, these knockout cell lines allow researchers to study the functional roles of FAM83D in vital biological pathways and disease contexts.

The primary function of FAM83D Gene Knockout Cell Lines is to facilitate the dissection of cellular mechanisms associated with cancer and other pathologies where FAM83D plays a contributory role. With the knockout of this gene, researchers can assess downstream effects on signaling pathways such as the MAPK and PI3K/Akt pathways, often deregulated in malignancies. This valuable tool is essential for unraveling the complexities of tumorigenesis and potential therapeutic avenues targeting FAM83D.

In terms of scientific importance, these cell lines can be utilized in both basic and translational research settings. They serve as an essential model for understanding the molecular underpinnings of cancer, providing insights that are critical for developing innovative therapeutic strategies. As such, they hold the promise of accelerating drug discovery processes by allowing for high-throughput screening of compounds that may inhibit or modulate pathways influenced by FAM83D.

Compared to traditional cell lines that express FAM83D, our knockout cell lines boast the unique advantage of enabling more nuanced hepatological investigations. Researchers will find value in their ability to delineate the specific contributions of FAM83D to pathology without the confounding effects of gene expression. This specificity enhances experimental fidelity and leads to more reliable data.

For researchers and clinicians alike, the FAM83D Gene Knockout Cell Lines offer a highly relevant, robust model for advancing scientific knowledge and therapeutic development. Developed and validated by a team of experts, our products reflect our commitment to providing high-quality biological tools that empower innovation in the life sciences. Our company's extensive experience in cell line engineering underpins the reliability and applicability of our offerings, making us your trusted partner in cutting-edge research.

Please note that all services are for research use only. Not intended for any clinical use.

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