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FAM50B Knockout Cell Lines

Gene: FAM50B

Official Full Name: family with sequence similarity 50 member Bprovided by HGNC

Gene Summary: This gene contains an intronless ORF that arose from ancestral retroposition. The encoded protein is related to a plant protein that plays a role in the circadian clock. This gene is adjacent to a differentially methylated region (DMR) and is imprinted and paternally expressed in many tissues. [provided by RefSeq, Nov 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28197 FAM50B Knockout cell line (HeLa) Human FAM50B 1:3~1:6 Negative Online Inquiry
KO28198 FAM50B Knockout cell line (HEK293) Human FAM50B 1:3~1:6 Negative Online Inquiry
KO28199 FAM50B Knockout cell line (A549) Human FAM50B 1:3~1:4 Negative Online Inquiry

Background

FAM50B Gene Knockout Cell Lines are engineered cellular models in which the FAM50B gene has been deliberately disrupted, allowing researchers to investigate the gene’s role in various biological processes. This product is crafted using cutting-edge CRISPR-Cas9 gene-editing technology, which provides a precise and efficient method to knockout target genes. The specific mechanism hinges on the introduction of double-strand breaks at the FAM50B locus, leading to insertions or deletions during the DNA repair process, ultimately resulting in loss of function.

The scientific importance of FAM50B gene knockout lies in its implications for understanding cellular pathways related to gene regulation, cancer biology, and developmental processes. Research has suggested that FAM50B may play a crucial role in chromatin remodeling and transcriptional regulation, making these knockout cell lines invaluable tools in dissecting the pathways that govern gene expression and cellular differentiation. Applications extend beyond basic research; these cell lines can be pivotal in drug discovery and the development of targeted therapies, especially in the context of malignancies where FAM50B is implicated.

What sets our FAM50B Gene Knockout Cell Lines apart from other gene knockout products is their rigorous validation, including verification of knockout efficiency at both the genomic and proteomic levels. Additionally, our cell lines are optimized for consistent growth and high transfection efficacy, allowing for seamless integration into diverse experimental workflows.

For researchers and clinicians, the value of utilizing FAM50B Gene Knockout Cell Lines is profound—they provide a reliable model for probing the gene’s functional dynamics and facilitate a deeper understanding of its contributions to disease mechanisms. This can accelerate findings in areas like functional genomics and therapeutic development.

At our company, we pride ourselves on our expertise in producing high-quality biological products that empower scientific discovery. Our commitment to advancing genetic research is reflected in our meticulously crafted cell lines, ensuring that researchers have the resources necessary to drive innovation in their fields.

Please note that all services are for research use only. Not intended for any clinical use.

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