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FAM161B Knockout Cell Lines

Gene: FAM161B

Official Full Name: FAM161 centrosomal protein Bprovided by HGNC

Gene Summary: Predicted to be involved in cilium organization. Located in cytoplasmic microtubule. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24051 FAM161B Knockout cell line (HeLa) Human FAM161B 1:3~1:6 Negative Online Inquiry
KO24052 FAM161B Knockout cell line (HCT 116) Human FAM161B 1:2~1:4 Negative Online Inquiry
KO24053 FAM161B Knockout cell line (HEK293) Human FAM161B 1:3~1:6 Negative Online Inquiry
KO24054 FAM161B Knockout cell line (A549) Human FAM161B 1:3~1:4 Negative Online Inquiry

Background

FAM161B Gene Knockout Cell Lines are genetically engineered mammalian cell lines in which the FAM161B gene has been specifically disrupted or "knocked out." This innovative product enables researchers to investigate the physiological roles and molecular pathways associated with the FAM161B gene, which is implicated in various biological processes, including photoreceptor functions and retinal diseases. The knockout methodology employs advanced CRISPR-Cas9 gene editing technology, which allows for precise alterations in the genome, resulting in the complete ablation of the target gene's expression.

The key function of the FAM161B knockout cell lines lies in their ability to serve as a versatile platform for functional studies. By eliminating FAM161B expression, these cell lines facilitate investigations into the gene's contribution to cellular processes such as cell growth, survival, and differentiation. Furthermore, the loss of FAM161B can be used to model specific genetic disorders, particularly those related to retinal degeneration, allowing researchers to explore disease mechanisms and test therapeutic interventions.

Scientifically, the availability of FAM161B knockout cell lines is significant for both basic research and clinical applications, especially in the context of gene therapy and regenerative medicine. Researchers can utilize these models to screen small molecules or gene editing strategies aimed at rescuing the phenotypic defects associated with FAM161B deficits. Additionally, these cell lines stand out from alternative models because they provide a clean genetic background, reducing variability often seen with heterogenous systems.

The unique advantage of utilizing FAM161B knockout cell lines is their ability to streamline experimental workflows, enhance reproducibility, and accelerate the discovery of new therapeutic strategies. By addressing specific research questions with targeted precision, researchers can obtain clearer insights into the pathophysiology of diseases linked to FAM161B.

In conclusion, our company specializes in the development of cutting-edge genetic models and tools that empower scientists and clinicians in their quest for innovative solutions in biomedical research. The FAM161B Gene Knockout Cell Lines exemplify our commitment to providing highly relevant and scientifically rigorous products tailored to advance understanding in the field of genetics and disease research.

Please note that all services are for research use only. Not intended for any clinical use.

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