Gene: FAM161A
Official Full Name: FAM161 centrosomal protein Aprovided by HGNC
Gene Summary: This gene belongs to the FAM161 family. It is expressed mainly in the retina. Mouse studies suggested that this gene is involved in development of retinal progenitors during embryogenesis, and that its activity is restricted to mature photoreceptors after birth. Mutations in this gene cause autosomal recessive retinitis pigmentosa-28. Alternatively spliced transcript variants have been identified.[provided by RefSeq, Jan 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25148 | FAM161A Knockout cell line (HeLa) | Human | FAM161A | 1:3~1:6 | Negative | Online Inquiry |
KO25149 | FAM161A Knockout cell line (HCT 116) | Human | FAM161A | 1:2~1:4 | Negative | Online Inquiry |
KO25150 | FAM161A Knockout cell line (HEK293) | Human | FAM161A | 1:3~1:6 | Negative | Online Inquiry |
KO25151 | FAM161A Knockout cell line (A549) | Human | FAM161A | 1:3~1:4 | Negative | Online Inquiry |
FAM161A Gene Knockout Cell Lines are specially developed cellular models that have undergone precise genetic engineering to eliminate the expression of the FAM161A gene. This gene is implicated in various cellular processes and has been studied in the context of retinal degeneration and other neurodegenerative disorders. The knockout of FAM161A enables researchers to investigate the gene's functional role, elucidate disease mechanisms, and identify potential therapeutic targets.
The key function of these cell lines lies in their ability to mimic the biological conditions of diseases associated with FAM161A deficiencies. By utilizing CRISPR/Cas9 technology, these cell lines provide a reliable and reproducible platform for examining phenotypic and genotypic changes resulting from the absence of FAM161A. Researchers can utilize these cell lines to study cellular pathways affected by FAM161A, validate potential gene therapies, or screen for drugs that may restore cellular function in the absence of this critical gene.
The scientific importance of FAM161A Gene Knockout Cell Lines is profound. They provide valuable insights into the pathophysiology of conditions like retinitis pigmentosa and other forms of retinal dystrophy. In clinical research, they can be used for developing gene therapies and optimizing treatment strategies aimed at restoring vision in affected individuals.
Compared to alternative cell models, the FAM161A Gene Knockout Cell Lines offer unique advantages, including enhanced specificity in gene targeting, a fully characterized genetic background, and the ability to produce consistent and reproducible results. These attributes ensure that researchers can rely on these models for high-quality scientific outputs, taking their studies from the laboratory to potential clinical applications with confidence.
For researchers and clinicians dedicated to unraveling genetic disorders, these cell lines serve as an indispensable resource, greatly aiding in the exploration of therapeutic interventions. Our company is committed to advancing scientific research by providing high-quality biological products and exceptional support to the research community, ensuring that scientists can focus on their groundbreaking work with the best tools available.
Please note that all services are for research use only. Not intended for any clinical use.
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