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F2RL2 Knockout Cell Lines

Gene: F2RL2

Official Full Name: coagulation factor II thrombin receptor like 2provided by HGNC

Gene Summary: This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO37930 F2RL2 Knockout cell line (A549) Human F2RL2 1:3~1:4 Negative Online Inquiry

Background

F2RL2 Gene Knockout Cell Lines are specialized cell lines that have been genetically modified to disrupt or 'knock out' the function of the F2RL2 gene, which encodes a receptor implicated in various physiological responses, including inflammation and thrombosis. These cell lines serve as critical tools for studying the role of F2RL2 in cellular processes and disease mechanisms, enabling researchers to explore gene function, signaling pathways, and potential therapeutic targets.

The key function of these knockout cell lines lies in their ability to facilitate the investigation of F2RL2's involvement in key biological processes by comparing knockout cells to their wild-type counterparts. This gene knockout leads to the absence of F2RL2 expression, allowing researchers to observe changes in cell behavior, signaling cascades, and phenotype. By utilizing these cell lines, scientists can dissect the specific contributions of F2RL2 to conditions such as cardiovascular diseases, inflammatory responses, and cancer progression.

In the realm of scientific research, F2RL2 Gene Knockout Cell Lines represent an invaluable resource for both basic and translational studies. Their application extends to drug discovery, where understanding the role of F2RL2 in different pathologies can inform the development of targeted therapies. These cell lines also hold utility in preclinical models, allowing for in vivo studies and fostering the translation of animal findings to human applications.

Compared to traditional methods, such as RNA interference (RNAi), the F2RL2 Gene Knockout approach offers several advantages. Specifically, the knockout cells provide a permanent disruption of gene expression, eliminating off-target effects often associated with transient techniques like siRNA. This stability allows for prolonged experimentation and robust data generation, enhancing the reliability of study outcomes.

Researchers and clinicians will find exceptional value in the F2RL2 Gene Knockout Cell Lines, as they provide a clear and effective means to further understand the complexities of cellular interactions and disease mechanisms influenced by F2RL2. This can lead to advancements in therapeutic strategies, ultimately improving patient care.

Our company specializes in producing high-quality genetic models and cell lines designed for rigorous scientific investigation. With our expertise in cellular biology and genetic engineering, we ensure that our F2RL2 Gene Knockout Cell Lines meet the highest standards of reliability and performance, enabling in-depth research and discovery for our customers.

Please note that all services are for research use only. Not intended for any clinical use.

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