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EXOC7 Knockout Cell Lines

Gene: EXOC7

Official Full Name: exocyst complex component 7provided by HGNC

Gene Summary: The protein encoded by this gene is a component of the exocyst complex. The exocyst complex plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. The encoded protein is required for assembly of the exocyst complex and docking of the complex to the plasma membrane. The encoded protein may also play a role in pre-mRNA splicing through interactions with pre-mRNA-processing factor 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Nov 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29571 EXOC7 Knockout cell line (HeLa) Human EXOC7 1:3~1:6 Negative Online Inquiry
KO29572 EXOC7 Knockout cell line (HCT 116) Human EXOC7 1:2~1:4 Negative Online Inquiry
KO29573 EXOC7 Knockout cell line (HEK293) Human EXOC7 1:3~1:6 Negative Online Inquiry
KO29574 EXOC7 Knockout cell line (A549) Human EXOC7 1:3~1:4 Negative Online Inquiry

Background

EXOC7 Gene Knockout Cell Lines are engineered cellular systems that have undergone precise genetic modifications to remove the EXOC7 gene, a critical component of the exocyst complex involved in exocytosis. This specialized gene knockout model enables researchers to investigate the functional roles of EXOC7 in various cellular processes, including protein secretion, cell signaling, and membrane trafficking, thereby offering insights into fundamental biological pathways and disease mechanisms.

The primary mechanism through which EXOC7 Knockout Cell Lines operate involves the disruption of the exocyst complex assembly, impacting vesicle transport and fusion dynamics. This alteration leads to specific phenotypic changes that can be closely monitored, allowing researchers to ascertain the gene's role in physiological and pathological states. By leveraging these knockout models, scientists can explore hypotheses regarding cellular behavior in response to various stimuli, making them invaluable for studies ranging from basic cell biology to complex disease processes.

The scientific importance of EXOC7 Gene Knockout Cell Lines is underscored by their applications in both research and clinical settings, including drug discovery and therapeutic development. Researchers can utilize these models to screen for novel compounds that target exocyst dysfunction and contribute to the development of treatments for conditions such as cancer, neurodegenerative diseases, and metabolic disorders.

What sets EXOC7 Gene Knockout Cell Lines apart from traditional genetic models is their precision and the level of customization available. Unlike general gene knockdown approaches that may yield ambiguous results due to residual gene activity, knockout lines provide a definitive assessment of gene function. Additionally, our cell lines are rigorously validated and characterized, ensuring high reproducibility and reliability in experimental outcomes.

For researchers and clinicians focused on elucidating the role of exocytosis and associated signaling pathways, EXOC7 Gene Knockout Cell Lines offer a unique and effective tool. By integrating foundational genetic knowledge with cutting-edge technology, our product empowers scientists to make groundbreaking discoveries that can lead to innovative treatments and therapeutic strategies.

Our company specializes in the development of advanced biological models, and we are committed to providing high-quality research tools that meet the evolving needs of the scientific community. With an emphasis on excellence and reliability, our offerings are designed to support cutting-edge research across multiple domains of life science.

Please note that all services are for research use only. Not intended for any clinical use.

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