Gene: ESYT1
Official Full Name: extended synaptotagmin 1provided by HGNC
Gene Summary: Enables identical protein binding activity and phospholipid transfer activity. Involved in intermembrane lipid transfer. Located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29401 | ESYT1 Knockout cell line (HeLa) | Human | ESYT1 | 1:3~1:6 | Negative | Online Inquiry |
KO29402 | ESYT1 Knockout cell line (HCT 116) | Human | ESYT1 | 1:2~1:4 | Negative | Online Inquiry |
KO29403 | ESYT1 Knockout cell line (HEK293) | Human | ESYT1 | 1:3~1:6 | Negative | Online Inquiry |
KO29404 | ESYT1 Knockout cell line (A549) | Human | ESYT1 | 1:3~1:4 | Negative | Online Inquiry |
ESYT1 Gene Knockout Cell Lines are genetically modified cell lines engineered to have a complete disruption of the ESYT1 gene, which plays a crucial role in membrane trafficking and lipid metabolism. By systematically deleting this gene, researchers can study its functional role within various cellular processes, such as lipogenesis, lipid droplet formation, and cellular stress responses, thus providing powerful tools for investigating the underlying mechanisms of lipid-related disorders.
The primary function of these cell lines lies in their ability to mimic pathological states, allowing for the assessment of ESYT1’s specific contributions to cellular physiology. Mechanistically, cell lines with the ESYT1 gene knocked out demonstrate altered lipid profiles, abnormal membrane dynamics, and have been implicated in the development of metabolic diseases. This specificity provides a clearer avenue for research into potential therapeutic interventions targeting lipid metabolism.
The scientific importance of these knockout cell lines is highlighted through multiple applications in both basic and translational research. They are instrumental for drug discovery, allowing researchers to identify novel compounds that may restore normal functions disrupted by ESYT1 deficiency. Additionally, they serve as vital models for studying various diseases, including obesity, diabetes, and certain forms of cancer linked to lipid dysregulation.
What sets ESYT1 Gene Knockout Cell Lines apart from traditional cell lines is their precise genetic modification, which enhances experimental reproducibility and minimizes variability. Unlike alternative models, these cell lines offer a standardized system for the exploration of complex biological questions related to lipid dynamics, enabling faster and more reliable results.
Researchers and clinicians will find significant value in utilizing ESYT1 Gene Knockout Cell Lines as they facilitate deeper insights into lipid-related pathophysiology and potential therapeutic strategies. By harnessing these innovative models, users can streamline their research processes and enhance the translational potential of their findings.
Our company specializes in supplying high-quality, genetically engineered cell lines to the scientific community, backed by extensive expertise in molecular genetics and cell biology. We are committed to enabling groundbreaking research, and our ESYT1 Gene Knockout Cell Lines exemplify our dedication to providing tools that empower scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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