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ERMP1 Knockout Cell Lines

Gene: ERMP1

Official Full Name: endoplasmic reticulum metallopeptidase 1provided by HGNC

Gene Summary: Predicted to enable metal ion binding activity and metalloexopeptidase activity. Involved in cellular response to oxidative stress. Acts upstream of or within endoplasmic reticulum unfolded protein response. Located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17897 ERMP1 Knockout cell line (HeLa) Human ERMP1 1:3~1:6 Negative Online Inquiry
KO17898 ERMP1 Knockout cell line (HCT 116) Human ERMP1 1:2~1:4 Negative Online Inquiry
KO17899 ERMP1 Knockout cell line (HEK293) Human ERMP1 1:3~1:6 Negative Online Inquiry
KO17900 ERMP1 Knockout cell line (A549) Human ERMP1 1:3~1:4 Negative Online Inquiry

Background

ERMP1 Gene Knockout Cell Lines are genetically modified cellular systems specifically designed to facilitate the study of the ERMP1 gene's functions in various biological processes. These cell lines have undergone targeted genetic deletion, effectively rendering the ERMP1 gene inactive. This precise manipulation enables researchers to investigate the consequences of ERMP1 loss on cellular mechanisms, signaling pathways, and disease progression, particularly in the context of inflammation and immune responses.

The primary mechanism underlying the utility of ERMP1 Gene Knockout Cell Lines lies in their ability to mimic disease states and elucidate gene function. By observing cellular behaviors in the absence of the ERMP1 protein, researchers can gain insights into the protein's role in various physiological and pathological conditions. This makes the knockout cell lines invaluable tools in dissecting complex molecular interactions, understanding gene redundancy, and exploring compensatory mechanisms that may arise from the knockout event.

The scientific significance of these cell lines extends to both fundamental research and translational applications. They serve as a platform for drug discovery, allowing for the screening of therapeutic compounds that may target pathways influenced by the ERMP1 gene. Additionally, in clinical settings, these cell lines can assist in biomarker discovery and provide a framework for developing novel therapies aimed at conditions where ERMP1 plays a pivotal role.

Compared to traditional wild-type cell lines or less specific knockout models, ERMP1 Gene Knockout Cell Lines offer specificity and reliability. Their creation follows stringent verification protocols to ensure accurate gene targeting, resulting in reproducible experimental outcomes. This specificity translates into enhanced data quality, minimizing confounding variables associated with off-target effects commonly seen in other genetic manipulation methods.

For researchers and clinicians aiming for clarity in their investigations of ERMP1, these cell lines are a valuable asset that streamline and enhance the research process. By facilitating a deeper understanding of gene function and associated biological pathways, ERMP1 Gene Knockout Cell Lines contribute significantly to advancing biomedical research.

Our company leverages extensive expertise in genetic engineering and cell line development, ensuring that we provide high-quality, reliable tools to support our users' research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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