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ERI3 Knockout Cell Lines

Gene: ERI3

Official Full Name: ERI1 exoribonuclease family member 3provided by HGNC

Gene Summary: Enables RNA binding activity. Predicted to be involved in exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17910 ERI3 Knockout cell line (HeLa) Human ERI3 1:3~1:6 Negative Online Inquiry
KO17911 ERI3 Knockout cell line (HCT 116) Human ERI3 1:2~1:4 Negative Online Inquiry
KO17912 ERI3 Knockout cell line (HEK293) Human ERI3 1:3~1:6 Negative Online Inquiry
KO17913 ERI3 Knockout cell line (A549) Human ERI3 1:3~1:4 Negative Online Inquiry

Background

ERI3 Gene Knockout Cell Lines are advanced biological research tools specifically designed for investigating the functional roles of the ERI3 gene in various cellular contexts. These cell lines have been genetically modified using CRISPR-Cas9 technology to create precise knockouts of the ERI3 gene, which encodes a member of the RNA editing enzyme family. By eliminating the expression of this gene, researchers can study the downstream effects on cellular functions, signaling pathways, and gene expression profiles, enabling a deeper understanding of its biological significance.

The mechanism by which the ERI3 Gene Knockout Cell Lines operate hinges on the complete absence of ERI3 protein expression, allowing scientists to observe cellular behavior under conditions devoid of this specific gene influence. This enables the exploration of crucial aspects such as RNA metabolism, immune response modulation, and potential roles in various diseases, particularly those linked to RNA processing and surveillance mechanisms.

In terms of scientific importance, these knockout cell lines are invaluable in both research and clinical settings. They provide a platform for elucidating the molecular pathways involved in gene regulation and pathogenesis, making them suitable for drug discovery, target validation, and genetic studies. Additionally, they can assist in the development of therapeutic strategies aimed at conditions where ERI3 plays a critical role.

One of the distinguishing advantages of our ERI3 Gene Knockout Cell Lines over alternative products is their high specificity and reliability, ensured through precision engineering and rigorous validation protocols. Unlike non-targeted approaches, these cell lines offer reproducible results, making them a preferred choice for researchers looking for consistent and precise data.

For researchers and clinicians, the value of our ERI3 Gene Knockout Cell Lines lies in their potential to drive significant scientific breakthroughs and enhance understanding of gene function, which can lead to innovative therapies and improved patient outcomes. The product addresses a critical need for high-quality knockout models in molecular genetics.

Our company prides itself on its extensive expertise in the development of genetically modified models and commitment to advancing biological research. We aim to provide researchers with the tools they need to uncover the complexities of gene function and contribute to the broader field of biomedical science.

Please note that all services are for research use only. Not intended for any clinical use.

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